Nonalcoholic fatty liver disease (NAFLD) and alcohol-related liver disease (ALD) are the
leading causes of chronic liver disease worldwide. NAFLD and ALD share …

Atherosclerosis is a chronic inflammatory disease characterized by the accumulation of fatty
deposits in the inner walls of vessels. These plaques restrict blood flow and lead to …

Most metastatic cancers remain incurable due to the emergence of apoptosis-resistant
clones, fuelled by intratumour heterogeneity and tumour evolution. To improve treatment …

The ability of mammals to mount adaptive immune responses culminating with the
establishment of immunological memory is predicated on the ability of the mature T cell …

Tumor hypoxia resulting from abnormal and dysfunctional tumor vascular network poses a
substantial obstacle to immunotherapy. In fact, hypoxia creates an immunosuppressive …

Type I interferon (IFN) is a class of proinflammatory cytokines with a dual role on malignant
transformation, tumor progression, and response to therapy. On the one hand, robust, acute …

Macroautophagy/autophagy is a complex degradation process with a dual role in cell death
that is influenced by the cell types that are involved and the stressors they are exposed to …

Ferroptosis is an iron-and reactive oxygen species (ROS)-dependent form of regulated cell
death, that has been implicated in Alzheimer's disease and Parkinson's disease. Inhibition of …

Immunogenic cell death (ICD), which results from insufficient cellular adaptation to specific
stressors, occupies a central position in the development of novel anticancer treatments …

Cancer cells undergoing immunogenic cell death (ICD) can initiate adaptive immune
responses against dead cell‐associated antigens, provided that (1) said antigens are not …