Simple Summary Inflammation and free radicals can stimulate cell self-destruction.
Inflammation and cell death are vital aspects of most diseases. Accumulation of cell damage …

Inflammatory bowel disease (IBD) is a chronic inflammatory condition that is influenced by
various factors, including environmental factors, immune responses, and genetic elements …

Time-of-day significantly influences the severity and incidence of stroke. Evidence has
emerged not only for circadian governance over stroke risk factors, but also for important …

DNA repair is essential for successful propagation of genetic material and fidelity of
transcription. Nucleotide excision repair (NER) is one of the earliest DNA repair …

Ferroptosis has attracted attention throughout the last decade because of its tremendous
clinical importance. Here, we review the rapidly growing body of literature on how inhibition …

BAX and BAK are proapoptotic members of the BCL2 family that directly mediate
mitochondrial outer membrane permeabilition (MOMP), a central step in apoptosis …

Background Head and neck squamous cell carcinoma (HNSCC) is characterized by high
proliferation and limited differentiation. The altered expression of the p53 family members …

Gasdermins (GSDMs) serve as pivotal executors of pyroptosis and play crucial roles in host
defence, cytokine secretion, innate immunity, and cancer. However, excessive or …

Background Acute cholangitis is a severe, life-threatening infection of the biliary system that
requires early diagnosis and treatment. The Tokyo Guidelines recommend a combination of …

Cell death can be classified into two primary categories: accidental cell death and regulated
cell death (RCD). Within RCD, there are distinct apoptotic and non-apoptotic cell death …