Epithelial tissue homeostasis is closely associated with the self-renewal and differentiation
behaviors of epithelial stem cells (ESCs). p63, a well-known marker of ESCs, is an …

Neuropathic pain is a common and debilitating modality of chronic pain induced by a lesion
or disease of the somatosensory nervous system. Albeit the elucidation of numerous …

Colorectal cancer is a major public health concern, with increasing incidence and mortality
rates worldwide. Environmental factors, including exposure to toxic metals, such as lead …

Immunogenic cell death (ICD), which results from insufficient cellular adaptation to specific
stressors, occupies a central position in the development of novel anticancer treatments …

Accumulating evidence suggests that metabolic rewiring in malignant cells supports tumour
progression not only by providing cancer cells with increased proliferative potential and an …

Ferroptosis is a type of regulated cell death characterized by lipid peroxidation and
subsequent damage to the plasma membrane. Here, we report a ferroptosis resistance …

Triple-negative breast cancer (TNBC) is the most aggressive subtype of mammary
carcinoma. Here, we describe a case of an 81-year-old female diagnosed with ductal triple …

Genomic instability, a hallmark of cancer, is a direct consequence of the inactivation of the
tumor suppressor protein p53. Genetically modified mouse models and human tumor …

Cancer cells undergoing immunogenic cell death (ICD) can initiate adaptive immune
responses against dead cell‐associated antigens, provided that (1) said antigens are not …

Sterols, including β‐sitosterol, are essential components of cellular membranes in both plant
and animal cells. Despite being a major phytosterol in various plant materials …