[HTML][HTML] Hepatitis C virus and hepatocellular carcinoma: a narrative review

P Axley, Z Ahmed, S Ravi, AK Singal - Journal of clinical and …, 2018 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is a leading cause of liver-related death worldwide.
Hepatitis C virus (HCV) infection is a major cause of advanced hepatic fibrosis and cirrhosis …

Incidence of hepatocellular carcinoma after direct antiviral therapy for HCV in patients with cirrhosis included in surveillance programs

P Nahon, R Layese, V Bourcier, C Cagnot, P Marcellin… - Gastroenterology, 2018 - Elsevier
Background & Aims Retrospective studies have found an unexpectedly high incidence of
hepatocellular carcinoma (HCC) among patients with hepatitis C virus (HCV)-associated …

Fibrosis regression after eradication of hepatitis C virus: from bench to bedside

DC Rockey, SL Friedman - Gastroenterology, 2021 - Elsevier
Hepatitis C virus (HCV) infection and its complications have been the major cause of
cirrhosis and its complications for several decades in the Western world. Until recently …

Delisting of liver transplant candidates with chronic hepatitis C after viral eradication: a European study

LS Belli, M Berenguer, PA Cortesi, M Strazzabosco… - Journal of …, 2016 - Elsevier
Background & Aims All oral direct acting antivirals (DAA) have been shown to improve the
liver function of patients with decompensated cirrhosis but it is presently unknown whether …

Impact of DAAs on liver transplantation: major effects on the evolution of indications and results. An ELITA study based on the ELTR registry

LS Belli, G Perricone, R Adam, PA Cortesi… - Journal of …, 2018 - Elsevier
Background & Aims Direct-acting antivirals (DAAs) have dramatically improved the outcome
of patients with hepatitis C virus (HCV) infection including those with decompensated …

[HTML][HTML] Clinical outcomes following DAA therapy in patients with HCV-related cirrhosis depend on disease severity

LAP Krassenburg, R Maan, A Ramji, MP Manns… - Journal of …, 2021 - Elsevier
Background & Aims HCV-infected patients with cirrhosis achieve high sustained virological
response (SVR) rates with direct-acting antivirals (DAAs) even after hepatic …

What are the benefits of a sustained virologic response to direct-acting antiviral therapy for hepatitis C virus infection?

GN Ioannou, JJ Feld - Gastroenterology, 2019 - Elsevier
Direct-acting antiviral (DAA) regimens are safe and effective at eradicating hepatitis C virus
(HCV) infection. Unfortunately, DAAs remain expensive, so treatment of all HCV-infected …

[PDF][PDF] Reduction in liver transplant wait‐listing in the era of direct‐acting antiviral therapy

JA Flemming, WR Kim, CL Brosgart, NA Terrault - Hepatology, 2017 - Wiley Online Library
Direct‐acting antiviral (DAA) therapy, recently approved for patients with decompensated
cirrhosis (DC) secondary to hepatitis C virus (HCV), is associated with improved hepatic …

Direct-acting antivirals after successful treatment of early hepatocellular carcinoma improve survival in HCV-cirrhotic patients

G Cabibbo, C Celsa, V Calvaruso, S Petta… - Journal of …, 2019 - Elsevier
Background & Aims The effectiveness of direct-acting antivirals (DAAs) against hepatitis C
virus (HCV), following successful treatment of early hepatocellular carcinoma (HCC), has …

Metabolomics in infectious diseases and drug discovery

V Tounta, Y Liu, A Cheyne, G Larrouy-Maumus - Molecular omics, 2021 - pubs.rsc.org
Metabolomics has emerged as an invaluable tool that can be used along with genomics,
transcriptomics and proteomics to understand host–pathogen interactions at small-molecule …