[HTML][HTML] Direct-acting antiviral agents for hepatitis C virus infection—From drug discovery to successful implementation in clinical practice
C Dietz, B Maasoumy - Viruses, 2022 - mdpi.com
Today, hepatitis C virus infection affects up to 1.5 million people per year and is responsible
for 29 thousand deaths per year. In the 1970s, the clinical observation of unclear, transfusion …
for 29 thousand deaths per year. In the 1970s, the clinical observation of unclear, transfusion …
Time association between hepatitis C therapy and hepatocellular carcinoma emergence in cirrhosis: relevance of non-characterized nodules
Background & Aims Despite direct-acting antivirals being highly effective at eradicating
hepatitis C virus infection, their impact on the development of hepatocellular carcinoma …
hepatitis C virus infection, their impact on the development of hepatocellular carcinoma …
Curbing the hepatitis C virus epidemic in Pakistan: the impact of scaling up treatment and prevention for achieving elimination
AG Lim, H Qureshi, H Mahmood… - International journal …, 2018 - academic.oup.com
Abstract Background The World Health Organization (WHO) has developed a global health
strategy to eliminate viral hepatitis. We project the treatment and prevention requirements to …
strategy to eliminate viral hepatitis. We project the treatment and prevention requirements to …
[PDF][PDF] Treatment of hepatitis C virus infection in patients with cirrhosis and predictive value of model for end‐stage liver disease: Analysis of data from the Hepa‐C …
C Fernandez Carrillo, S Lens, E Llop, JM Pascasio… - …, 2017 - Wiley Online Library
Direct‐acting antiviral agents (DAAs) are highly effective and well tolerated in patients with
chronic hepatitis C virus infection, including those with compensated cirrhosis. However …
chronic hepatitis C virus infection, including those with compensated cirrhosis. However …
Direct-acting antivirals: the endgame for hepatitis C?
R D'Ambrosio, E Degasperi, M Colombo… - Current opinion in …, 2017 - Elsevier
Highlights•DAAs for HCV treatment include protease (NS3/4A) inhibitors, RNA-dependent
polymerase (NS5B) inhibitors and NS5A inhibitors.•The combination of DAA owning to …
polymerase (NS5B) inhibitors and NS5A inhibitors.•The combination of DAA owning to …
Viral hepatitis: guidelines by the American society of transplantation infectious disease community of practice
H Te, K Doucette - Clinical Transplantation, 2019 - Wiley Online Library
These updated guidelines from the Infectious Diseases Community of Practice of the
American Society of Transplantation review the diagnosis, prevention, and management of …
American Society of Transplantation review the diagnosis, prevention, and management of …
Sofosbuvir plus velpatasvir treatment for hepatitis C virus in patients with decompensated cirrhosis: a Japanese real-world multicenter study
Y Tahata, H Hikita, S Mochida, N Kawada… - Journal of …, 2021 - Springer
Background Real-world data on the efficacy and safety of sofosbuvir plus velpatasvir
(SOF/VEL) treatment for patients with hepatitis C virus (HCV)-related decompensated …
(SOF/VEL) treatment for patients with hepatitis C virus (HCV)-related decompensated …
Treatment of chronic hepatitis C: efficacy, side effects and complications
L Sandmann, B Schulte, MP Manns, B Maasoumy - Visceral medicine, 2019 - karger.com
Background: Chronic hepatitis C virus (HCV) infection can lead to liver cirrhosis and its
complications. Viral eradication is essential to prevent disease progression and reduces …
complications. Viral eradication is essential to prevent disease progression and reduces …
Treatment with direct-acting antivirals improves the clinical outcome in patients with HCV-related decompensated cirrhosis: results from an Italian real-life cohort (Liver …
I Gentile, R Scotto, C Coppola, L Staiano… - Hepatology …, 2019 - Springer
Abstract Background Direct-acting antivirals (DAAs) are safe and effective for the treatment
of HCV infection. However, data regarding their efficacy in patients with Child–Pugh B …
of HCV infection. However, data regarding their efficacy in patients with Child–Pugh B …
Systematic review with meta‐analysis: recurrence of hepatocellular carcinoma following direct‐acting antiviral therapy
N Saraiya, AC Yopp, NE Rich… - Alimentary …, 2018 - Wiley Online Library
Background Although studies suggest decreased incident hepatocellular carcinoma (HCC)
after direct‐acting antivirals (DAA), data are conflicting regarding HCC recurrence and …
after direct‐acting antivirals (DAA), data are conflicting regarding HCC recurrence and …