[HTML][HTML] mRNA-based therapeutics: powerful and versatile tools to combat diseases

S Qin, X Tang, Y Chen, K Chen, N Fan… - Signal transduction and …, 2022 - nature.com
The therapeutic use of messenger RNA (mRNA) has fueled great hope to combat a wide
range of incurable diseases. Recent rapid advances in biotechnology and molecular …

Harnessing nanomaterials for cancer sonodynamic immunotherapy

S Liang, J Yao, D Liu, L Rao, X Chen… - Advanced …, 2023 - Wiley Online Library
Immunotherapy has made remarkable strides in cancer therapy over the past decade.
However, such emerging therapy still suffers from the low response rates and immune …

Mechanisms of immunothrombosis in vaccine-induced thrombotic thrombocytopenia (VITT) compared to natural SARS-CoV-2 infection

D McGonagle, G De Marco, C Bridgewood - Journal of autoimmunity, 2021 - Elsevier
Herein, we consider venous immunothrombotic mechanisms in SARS-CoV-2 infection and
anti-SARS-CoV-2 DNA vaccination. Primary SARS-CoV-2 infection with systemic viral RNA …

[HTML][HTML] Vaccine adjuvants: Mechanisms and platforms

T Zhao, Y Cai, Y Jiang, X He, Y Wei, Y Yu… - Signal transduction and …, 2023 - nature.com
Adjuvants are indispensable components of vaccines. Despite being widely used in
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …

[HTML][HTML] MoS2-based nanocomposites for cancer diagnosis and therapy

J Wang, L Sui, J Huang, L Miao, Y Nie, K Wang… - Bioactive Materials, 2021 - Elsevier
Molybdenum is a trace dietary element necessary for the survival of humans. Some
molybdenum-bearing enzymes are involved in key metabolic activities in the human body …

In response to precision medicine: Current subcellular targeting strategies for cancer therapy

Z Li, J Zou, X Chen - Advanced Materials, 2023 - Wiley Online Library
Emerging as a potent anticancer treatment, subcellular targeted cancer therapy has drawn
increasing attention, bringing great opportunities for clinical application. Here, two targeting …

[HTML][HTML] COVID-19 vaccines: Current status and implication for use in Indonesia

Y Ophinni, AS Hasibuan, A Widhani… - Acta Medica …, 2020 - actamedindones.org
Abstract The coronavirus disease 2019 (COVID-19) has inflicted catastrophic damages in
public health, economic and social stability—putting life globally on hold in 2020 and …

Vaccine adjuvants: Understanding the structure and mechanism of adjuvanticity

S Shi, H Zhu, X Xia, Z Liang, X Ma, B Sun - Vaccine, 2019 - Elsevier
In conjugate, inactivated, recombinant, and toxoid vaccines, adjuvants are extensively and
essentially used for enhanced and long-lasting protective immune responses. Depending …

Compound copper chalcogenide nanocrystals

C Coughlan, M Ibanez, O Dobrozhan, A Singh… - Chemical …, 2017 - ACS Publications
This review captures the synthesis, assembly, properties, and applications of copper
chalcogenide NCs, which have achieved significant research interest in the last decade due …

Separable microneedle patch to protect and deliver DNA nanovaccines against COVID-19

Y Yin, W Su, J Zhang, W Huang, X Li, H Ma, M Tan… - ACS …, 2021 - ACS Publications
The successful control of coronavirus disease 2019 (COVID-19) pandemic is not only relying
on the development of vaccines, but also depending on the storage, transportation, and …