Whole-genome sequencing in outbreak analysis
CA Gilchrist, SD Turner, MF Riley… - Clinical microbiology …, 2015 - Am Soc Microbiol
In addition to the ever-present concern of medical professionals about epidemics of
infectious diseases, the relative ease of access and low cost of obtaining, producing, and …
infectious diseases, the relative ease of access and low cost of obtaining, producing, and …
The application of genomics to tracing bacterial pathogen transmission
NJ Croucher, X Didelot - Current Opinion in Microbiology, 2015 - Elsevier
Highlights•WGS is unique in offering the resolution to investigate direct pathogen
transmission.•Confirmation of direct transmission needs multiple sequences from donors & …
transmission.•Confirmation of direct transmission needs multiple sequences from donors & …
Bacterial whole-genome sequencing revisited: portable, scalable, and standardized analysis for typing and detection of virulence and antibiotic resistance genes
SR Leopold, RV Goering, A Witten… - Journal of clinical …, 2014 - Am Soc Microbiol
Multidrug-resistant nosocomial pathogens present a major burden for hospitals. Rapid
cluster identification and pathogen profiling, ie, of antibiotic resistance and virulence genes …
cluster identification and pathogen profiling, ie, of antibiotic resistance and virulence genes …
Longitudinal genomic surveillance of MRSA in the UK reveals transmission patterns in hospitals and the community
Genome sequencing has provided snapshots of the transmission of methicillin-resistant
Staphylococcus aureus (MRSA) during suspected outbreaks in isolated hospital wards …
Staphylococcus aureus (MRSA) during suspected outbreaks in isolated hospital wards …
Bacterial sepsis and meningitis
V Nizet, J Klein - Infectious diseases of the fetus and newborn …, 2014 - books.google.com
Bacterial sepsis in the neonate is a clinical syndrome characterized by systemic signs of
infection and accompanied by bacteremia in the first month of life. Meningitis in the neonate …
infection and accompanied by bacteremia in the first month of life. Meningitis in the neonate …
Whole-Genome Sequencing Shows That Patient-to-Patient Transmission Rarely Accounts for Acquisition of Staphylococcus aureus in an Intensive Care Unit
Abstract Background. Strategies to prevent Staphylococcus aureus infection in hospitals
focus on patient-to-patient transmission. We used whole-genome sequencing to investigate …
focus on patient-to-patient transmission. We used whole-genome sequencing to investigate …
[HTML][HTML] Simultaneous inference of phylogenetic and transmission trees in infectious disease outbreaks
Whole-genome sequencing of pathogens from host samples becomes more and more
routine during infectious disease outbreaks. These data provide information on possible …
routine during infectious disease outbreaks. These data provide information on possible …
A shared population of epidemic methicillin-resistant Staphylococcus aureus 15 circulates in humans and companion animals
Methicillin-resistant Staphylococcus aureus (MRSA) is a global human health problem
causing infections in both hospitals and the community. Companion animals, such as cats …
causing infections in both hospitals and the community. Companion animals, such as cats …
The mother as most important risk factor for colonization of very low birth weight (VLBW) infants with extended-spectrum β-lactamase-producing Enterobacteriaceae …
LA Denkel, F Schwab, A Kola, R Leistner… - Journal of …, 2014 - academic.oup.com
Objectives This study aimed to determine the prevalence of and risk factors for colonization
with extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) and …
with extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) and …
[HTML][HTML] Improved characterisation of MRSA transmission using within-host bacterial sequence diversity
MD Hall, MTG Holden, P Srisomang, W Mahavanakul… - Elife, 2019 - elifesciences.org
Methicillin-resistant Staphylococcus aureus (MRSA) transmission in the hospital setting has
been a frequent subject of investigation using bacterial genomes, but previous approaches …
been a frequent subject of investigation using bacterial genomes, but previous approaches …