Effects of arachidonic acid metabolites on cardiovascular health and disease
Arachidonic acid (AA) is an essential fatty acid that is released by phospholipids in cell
membranes and metabolized by cyclooxygenase (COX), cytochrome P450 (CYP) enzymes …
membranes and metabolized by cyclooxygenase (COX), cytochrome P450 (CYP) enzymes …
Intake and metabolism of omega-3 and omega-6 polyunsaturated fatty acids: nutritional implications for cardiometabolic diseases
MB Schulze, AM Minihane, RNM Saleh… - The Lancet Diabetes & …, 2020 - thelancet.com
Prospective observational studies support the use of long-chain omega-3 polyunsaturated
fatty acids (PUFAs) in the primary prevention of atherosclerotic cardiovascular disease; …
fatty acids (PUFAs) in the primary prevention of atherosclerotic cardiovascular disease; …
Role of circulating polyunsaturated fatty acids on cardiovascular diseases risk: analysis using Mendelian randomization and fatty acid genetic association data from …
Background Despite early interest in the health effects of polyunsaturated fatty acids (PUFA),
there is still substantial controversy and uncertainty on the evidence linking PUFA to …
there is still substantial controversy and uncertainty on the evidence linking PUFA to …
Metabolomic epidemiology offers insights into disease aetiology
Metabolomic epidemiology is the high-throughput study of the relationship between
metabolites and health-related traits. This emerging and rapidly growing field has improved …
metabolites and health-related traits. This emerging and rapidly growing field has improved …
[HTML][HTML] Overall and abdominal obesity in relation to venous thromboembolism
Background Abdominal obesity has been shown to be a superior measure over overall
obesity for detecting cardiovascular risk. Objective We conducted this study to compare the …
obesity for detecting cardiovascular risk. Objective We conducted this study to compare the …
Mendelian randomization as a tool for causal inference in human nutrition and metabolism
SC Larsson - Current opinion in lipidology, 2021 - journals.lww.com
Mendelian randomization can be used as a tool to improve causal inference in
observational studies assessing the role of nutritional factors and metabolites in health and …
observational studies assessing the role of nutritional factors and metabolites in health and …
[HTML][HTML] Plasma phospholipid arachidonic acid in relation to non-alcoholic fatty liver disease: Mendelian randomization study
Objectives The role of plasma phospholipid arachidonic acid (AA) in the development of non-
alcoholic fatty liver disease (NALFD), cirrhosis, and liver cancer remains unclear. This study …
alcoholic fatty liver disease (NALFD), cirrhosis, and liver cancer remains unclear. This study …
The associations of plasma phospholipid arachidonic acid with cardiovascular diseases: a Mendelian randomization study
T Zhang, JV Zhao, CM Schooling - EBioMedicine, 2021 - thelancet.com
Background Arachidonic acid (AA), a major long-chain n-6 polyunsaturated fatty acid in
animal foods, has been linked to inflammation, coagulation, and testosterone, which might …
animal foods, has been linked to inflammation, coagulation, and testosterone, which might …
Fatty acid desaturase 1 (FADS1) is a cancer marker for patient survival and a potential novel target for precision cancer treatment
G Heravi, H Jang, X Wang, Z Long, Z Peng… - Frontiers in …, 2022 - frontiersin.org
Fatty Acid Desaturase-1 (FADS1) or delta 5 desaturase (D5D) is a rate-limiting enzyme
involved in the biosynthesis of long-chain polyunsaturated fatty acids (LC-PUFAs), ie …
involved in the biosynthesis of long-chain polyunsaturated fatty acids (LC-PUFAs), ie …
[HTML][HTML] Targeting metabolism in aortic aneurysm and dissection: from basic research to clinical applications
Q Wang, G Yesitayi, B Liu, D Siti… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Aortic aneurysm and dissection (AAD) are a group of insidious and lethal cardiovascular
diseases that characterized by seriously threatening the life and health of people, but lack …
diseases that characterized by seriously threatening the life and health of people, but lack …