Modification of associations between indoor particulate matter and systemic inflammation in individuals with COPD

E Busenkell, CM Collins, ML Moy, JE Hart… - Environmental …, 2022 - Elsevier
Rationale Little is known about personal characteristics and systemic responses to
particulate pollution in patients with COPD. Objectives Assess whether diabetes, obesity …

PP2A-mTOR-p70S6K/4E-BP1 axis regulates M1 polarization of pulmonary macrophages and promotes ambient particulate matter induced mouse lung injury

S Chen, L Chen, L Ye, Y Jiang, Q Li, H Zhang… - Journal of hazardous …, 2022 - Elsevier
To identify key signaling pathways involved in ambient particulate matter (PM)-induced
pulmonary injury, we generated a mouse model with myeloid-specific deletion of Ppp2r1a …

Exposure to air pollution exacerbates inflammation in rats with preexisting COPD

J Wang, Y Li, P Zhao, Y Tian, X Liu, H He… - Mediators of …, 2020 - Wiley Online Library
Particulate matter with an aerodynamic diameter equal or less than 2.5 micrometers (PM2.
5) is associated with the development of chronic obstructive pulmonary disease (COPD) …

Pulmonary emphysema subtypes defined by unsupervised machine learning on CT scans

ED Angelini, J Yang, PP Balte, EA Hoffman… - Thorax, 2023 - thorax.bmj.com
Background Treatment and preventative advances for chronic obstructive pulmonary
disease (COPD) have been slow due, in part, to limited subphenotypes. We tested if …

Association of dysanapsis with mortality among older adults

M Vameghestahbanati, C Sack… - European …, 2023 - Eur Respiratory Soc
Dysanapsis refers to an anthropometric mismatch of airway tree calibre that was first inferred
from inter-individual differences in maximum expiratory airflow among healthy adults [2] and …

Ambient air pollution and risk of respiratory infection among adults: evidence from the multiethnic study of atherosclerosis (MESA)

K Kirwa, CM Eckert, S Vedal… - BMJ open …, 2021 - bmjopenrespres.bmj.com
Background Air pollution may affect the risk of respiratory infection, though research has
focused on uncommon infections or infections in children. Whether ambient air pollutants …

Nanoparticle-exposure-triggered virus reactivation induces lung emphysema in mice

L Han, V Haefner, Y Yu, B Han, H Ren, M Irmler… - ACS …, 2023 - ACS Publications
Nanoparticles (NPs) released from engineered materials or combustion processes as well
as persistent herpesvirus infection are omnipresent and are associated with chronic lung …

Multi-Ethnic Study of Atherosclerosis (MESA) JACC Focus Seminar 5/8

MJ Blaha, AP DeFilippis - Journal of the American College of Cardiology, 2021 - jacc.org
Abstract The MESA (Multi-Ethnic Study of Atherosclerosis) is a National Heart, Lung, and
Blood Institute–sponsored prospective study aimed at studying the prevalence, progression …

[HTML][HTML] Prenatal exposure to air pollution and the risk of macrosomia: Identifying windows of susceptibility

L Shang, L Yang, W Yang, G Xie, R Wang, L Sun… - Science of The Total …, 2022 - Elsevier
This study explores the effects of prenatal exposure to air pollution on the risk of macrosomia
and its window of susceptibility. We conducted a retrospective cohort study utilizing records …

COVID-19 infections and fatalities developments: empirical evidence for OECD countries and newly industrialized economies

L Bretschger, E Grieg, PJJ Welfens, T Xiong - International Economics and …, 2020 - Springer
This paper presents empirical results on coronavirus infection and fatality rates from cross-
country regressions for OECD economies and a sample of middle-and high-income …