Alzheimer's disease (AD) stands as the predominant form of dementia, presenting significant
and escalating global challenges. Its etiology is intricate and diverse, stemming from a …

Biliverdin reductase-A (BVRA) is a multi-functional enzyme with a multitude of important
roles in physiologic redox homeostasis. Classically, BVRA is well known for converting the …

Synapse loss is the principal cause of cognitive decline in Alzheimer's disease (AD) and
related disorders (ADRD). Synapse development depends on the intricate dynamics of the …

The recent, controversial approval of antibody-based treatments for Alzheimer's disease
(AD) is fueling a heated debate on the molecular determinants of this condition. The …

Alzheimer's disease (AD) is a progressive and incurable neurodegenerative disorder that
primarily affects persons aged 65 years and above. It causes dementia with memory loss …

The most prevalent cause of dementia is Alzheimer's disease. Cognitive decline and
accelerating memory loss characterize it. Alzheimer's disease advances sequentially …

The amyloid-cascade-hypothesis of the pathogenesis of Alzheimer's disease (AD) was
introduced 32 years ago, in 1992. From early on, this clear and straight forward hypothesis …

Alzheimer's disease (AD) represents the most widespread neurodegenerative disorder,
distinguished by a gradual onset and slow progression, presenting a substantial challenge …

Alzheimer's disease (AD) causes a significant challenge to global healthcare systems, with
limited effective treatments available. This review examines the landscape of novel …

Abstract Background Patients with Alzheimer's Disease (AD) exhibit structural alterations of
the thalamus that correlate with clinical symptoms. However, given the anatomical …