The role of reactive oxygen species in antibiotic-mediated killing of bacteria
H Van Acker, T Coenye - Trends in microbiology, 2017 - cell.com
Recently, it was proposed that there is a common mechanism behind the activity of
bactericidal antibiotics, involving the production of reactive oxygen species (ROS). However …
bactericidal antibiotics, involving the production of reactive oxygen species (ROS). However …
Antifungal therapy: new advances in the understanding and treatment of mycosis
L Scorzoni, ACA de Paula e Silva, CM Marcos… - Frontiers in …, 2017 - frontiersin.org
The high rates of morbidity and mortality caused by fungal infections are associated with the
current limited antifungal arsenal and the high toxicity of the compounds. Additionally …
current limited antifungal arsenal and the high toxicity of the compounds. Additionally …
Antimicrobial peptide synergies for fighting infectious diseases
JT Mhlongo, AY Waddad, F Albericio… - Advanced …, 2023 - Wiley Online Library
Antimicrobial peptides (AMPs) are essential elements of thehost defense system.
Characterized by heterogenous structures and broad‐spectrumaction, they are promising …
Characterized by heterogenous structures and broad‐spectrumaction, they are promising …
Antimicrobial susceptibility testing of antimicrobial peptides to better predict efficacy
DK Mercer, MDT Torres, SS Duay, E Lovie… - Frontiers in cellular …, 2020 - frontiersin.org
During the development of antimicrobial peptides (AMP) as potential therapeutics,
antimicrobial susceptibility testing (AST) stands as an essential part of the process in …
antimicrobial susceptibility testing (AST) stands as an essential part of the process in …
Antifungal peptides: To be or not to be membrane active
M Rautenbach, AM Troskie, JA Vosloo - Biochimie, 2016 - Elsevier
Most antifungal peptides (AFPs), if not all, have membrane activity, while some also have
alternative targets. Fungal membranes share many characteristics with mammalian …
alternative targets. Fungal membranes share many characteristics with mammalian …
Synergistic combinations of antifungals and anti-virulence agents to fight against Candida albicans
Candida albicans, one of the pathogenic Candida species, causes high mortality rate in
immunocompromised and high-risk surgical patients. In the last decade, only one new class …
immunocompromised and high-risk surgical patients. In the last decade, only one new class …
The multifaceted antibacterial mechanisms of the pioneering peptide antibiotics tyrocidine and gramicidin S
Cyclic β-sheet decapeptides from the tyrocidine group and the homologous gramicidin S
were the first commercially used antibiotics, yet it remains unclear exactly how they kill …
were the first commercially used antibiotics, yet it remains unclear exactly how they kill …
[HTML][HTML] Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms
P Van Dijck, J Sjollema, BPA Cammue, K Lagrou… - Microbial Cell, 2018 - ncbi.nlm.nih.gov
Unlike superficial fungal infections of the skin and nails, which are the most common fungal
diseases in humans, invasive fungal infections carry high morbidity and mortality …
diseases in humans, invasive fungal infections carry high morbidity and mortality …
Tackling fungal resistance by biofilm inhibitors
S Wu, Y Wang, N Liu, G Dong… - Journal of Medicinal …, 2017 - ACS Publications
The high incidence and mortality of invasive fungal infections and serious drug resistance
have become a global public health issue. The ability of fungal cells to form biofilms is an …
have become a global public health issue. The ability of fungal cells to form biofilms is an …
Mechanisms of action of antimicrobial peptides ToAP2 and NDBP-5.7 against Candida albicans planktonic and biofilm cells
J do Nascimento Dias, C de Souza Silva… - Scientific reports, 2020 - nature.com
Candida albicans is a major cause of human infections, ranging from relatively simple to
treat skin and mucosal diseases to systemic life-threatening invasive candidiasis. Fungal …
treat skin and mucosal diseases to systemic life-threatening invasive candidiasis. Fungal …