Psychosis superspectrum I: Nosology, etiology, and lifespan development
This review describes the Hierarchical Taxonomy of Psychopathology (HiTOP) model of
psychosis-related psychopathology, the psychosis superspectrum. The HiTOP psychosis …
psychosis-related psychopathology, the psychosis superspectrum. The HiTOP psychosis …
Integrative brain network and salience models of psychopathology and cognitive dysfunction in schizophrenia
Brain network models of cognitive control are central to advancing our understanding of
psychopathology and cognitive dysfunction in schizophrenia. This review examines the role …
psychopathology and cognitive dysfunction in schizophrenia. This review examines the role …
Cognitive function and variability in antipsychotic drug–naive patients with first-episode psychosis: a systematic review and meta-analysis
M Lee, M Cernvall, J Borg, P Plavén-Sigray… - JAMA …, 2024 - jamanetwork.com
Importance Cognitive impairment contributes significantly to clinical outcome and level of
function in individuals with psychotic disorders. These impairments are present already at …
function in individuals with psychotic disorders. These impairments are present already at …
[HTML][HTML] Cognitive effects of lurasidone and cariprazine: a mini systematic review
M Olivola, N Bassetti, S Parente, V Arienti… - Current …, 2023 - ncbi.nlm.nih.gov
Cognitive deficits are associated with schizophrenia and show a progressive worsening,
often being unresponsive to treatment. New antipsychotic molecules acting as antagonist at …
often being unresponsive to treatment. New antipsychotic molecules acting as antagonist at …
Dementia among older people with schizophrenia: an update on recent studies
DH Adamowicz, EE Lee - Current opinion in psychiatry, 2023 - journals.lww.com
Recent evidence supports accelerated cognitive decline and brain changes in middle-aged
and older people with schizophrenia, relative to the general population. More research in …
and older people with schizophrenia, relative to the general population. More research in …
[HTML][HTML] Integrating Clinical Neuropsychology and Psychotic Spectrum Disorders: A Systematic Analysis of Cognitive Dynamics, Interventions, and Underlying …
Background and Objectives: The study aims to provide a comprehensive
neuropsychological analysis of psychotic spectrum disorders, including schizophrenia …
neuropsychological analysis of psychotic spectrum disorders, including schizophrenia …
Diagnostic specificity and association with cognition of molecular alterations in prefrontal somatostatin neurons in schizophrenia
SJ Dienel, KF Dowling, Z Barile, HH Bazmi… - JAMA …, 2023 - jamanetwork.com
Importance Individuals with schizophrenia (SZ) exhibit pronounced deficits in somatostatin
(SST) messenger RNA (mRNA) levels in the dorsolateral prefrontal cortex (DLPFC) …
(SST) messenger RNA (mRNA) levels in the dorsolateral prefrontal cortex (DLPFC) …
Reductions in synaptic marker SV2A in early-course Schizophrenia
Excess synaptic pruning during neurodevelopment has emerged as one of the leading
hypotheses on the causal mechanism for schizophrenia. It proposes that excess synaptic …
hypotheses on the causal mechanism for schizophrenia. It proposes that excess synaptic …
[HTML][HTML] Oscillatory deficits in the sub-chronic PCP rat model for schizophrenia are reversed by mGlu5 receptor-positive allosteric modulators VU0409551 and …
The cognitive deficits of schizophrenia are linked to imbalanced excitatory and inhibitory
signalling in the prefrontal cortex (PFC), disrupting gamma oscillations. We previously …
signalling in the prefrontal cortex (PFC), disrupting gamma oscillations. We previously …
[HTML][HTML] Diverging effects of mentalization based treatment for patients with borderline personality disorder and schizophrenia: an explorative comparison
JG Weijers, F van Kaam, JP Selten… - Frontiers in …, 2023 - frontiersin.org
Introduction There is robust evidence that both patients with schizophrenia (SCZ) and
borderline personality disorder (BPD) display mentalizing difficulties. Less is known …
borderline personality disorder (BPD) display mentalizing difficulties. Less is known …