Psychosis superspectrum I: Nosology, etiology, and lifespan development

KG Jonas, TD Cannon, AR Docherty, D Dwyer… - Molecular …, 2024 - nature.com
This review describes the Hierarchical Taxonomy of Psychopathology (HiTOP) model of
psychosis-related psychopathology, the psychosis superspectrum. The HiTOP psychosis …

Integrative brain network and salience models of psychopathology and cognitive dysfunction in schizophrenia

V Menon, L Palaniyappan, K Supekar - Biological Psychiatry, 2023 - Elsevier
Brain network models of cognitive control are central to advancing our understanding of
psychopathology and cognitive dysfunction in schizophrenia. This review examines the role …

Cognitive function and variability in antipsychotic drug–naive patients with first-episode psychosis: a systematic review and meta-analysis

M Lee, M Cernvall, J Borg, P Plavén-Sigray… - JAMA …, 2024 - jamanetwork.com
Importance Cognitive impairment contributes significantly to clinical outcome and level of
function in individuals with psychotic disorders. These impairments are present already at …

[HTML][HTML] Cognitive effects of lurasidone and cariprazine: a mini systematic review

M Olivola, N Bassetti, S Parente, V Arienti… - Current …, 2023 - ncbi.nlm.nih.gov
Cognitive deficits are associated with schizophrenia and show a progressive worsening,
often being unresponsive to treatment. New antipsychotic molecules acting as antagonist at …

Dementia among older people with schizophrenia: an update on recent studies

DH Adamowicz, EE Lee - Current opinion in psychiatry, 2023 - journals.lww.com
Recent evidence supports accelerated cognitive decline and brain changes in middle-aged
and older people with schizophrenia, relative to the general population. More research in …

[HTML][HTML] Integrating Clinical Neuropsychology and Psychotic Spectrum Disorders: A Systematic Analysis of Cognitive Dynamics, Interventions, and Underlying …

E Gkintoni, M Skokou, P Gourzis - Medicina, 2024 - mdpi.com
Background and Objectives: The study aims to provide a comprehensive
neuropsychological analysis of psychotic spectrum disorders, including schizophrenia …

Diagnostic specificity and association with cognition of molecular alterations in prefrontal somatostatin neurons in schizophrenia

SJ Dienel, KF Dowling, Z Barile, HH Bazmi… - JAMA …, 2023 - jamanetwork.com
Importance Individuals with schizophrenia (SZ) exhibit pronounced deficits in somatostatin
(SST) messenger RNA (mRNA) levels in the dorsolateral prefrontal cortex (DLPFC) …

Reductions in synaptic marker SV2A in early-course Schizophrenia

JH Yoon, Z Zhang, E Mormino, G Davidzon… - Journal of Psychiatric …, 2023 - Elsevier
Excess synaptic pruning during neurodevelopment has emerged as one of the leading
hypotheses on the causal mechanism for schizophrenia. It proposes that excess synaptic …

[HTML][HTML] Oscillatory deficits in the sub-chronic PCP rat model for schizophrenia are reversed by mGlu5 receptor-positive allosteric modulators VU0409551 and …

J Brown, B Grayson, JC Neill, M Harte, MJ Wall… - Cells, 2023 - mdpi.com
The cognitive deficits of schizophrenia are linked to imbalanced excitatory and inhibitory
signalling in the prefrontal cortex (PFC), disrupting gamma oscillations. We previously …

[HTML][HTML] Diverging effects of mentalization based treatment for patients with borderline personality disorder and schizophrenia: an explorative comparison

JG Weijers, F van Kaam, JP Selten… - Frontiers in …, 2023 - frontiersin.org
Introduction There is robust evidence that both patients with schizophrenia (SCZ) and
borderline personality disorder (BPD) display mentalizing difficulties. Less is known …