Flavonoids against the Warburg phenotype—Concepts of predictive, preventive and personalised medicine to cut the Gordian knot of cancer cell metabolism

M Samec, A Liskova, L Koklesova, SM Samuel, K Zhai… - Epma Journal, 2020 - Springer
The Warburg effect is characterised by increased glucose uptake and lactate secretion in
cancer cells resulting from metabolic transformation in tumour tissue. The corresponding …

Dietary phytochemicals in breast cancer research: anticancer effects and potential utility for effective chemoprevention

A Kapinova, P Kubatka, O Golubnitschaja… - … health and preventive …, 2018 - Springer
Cancerous tissue transformation developing usually over years or even decades of life is a
highly complex process involving strong stressors damaging DNA, chronic inflammation …

Anti-breast cancer effects of phytochemicals: primary, secondary, and tertiary care

A Mazurakova, L Koklesova, M Samec, E Kudela… - EPMA Journal, 2022 - Springer
Breast cancer incidence is actually the highest one among all cancers. Overall breast cancer
management is associated with challenges considering risk assessment and predictive …

Anticancer Activities of Thymus vulgaris L. in Experimental Breast Carcinoma In Vivo and In Vitro

P Kubatka, S Uramova, M Kello, K Kajo… - International journal of …, 2019 - mdpi.com
Naturally-occurring mixtures of phytochemicals present in plant foods are proposed to
possess tumor-suppressive activities. In this work, we aimed to evaluate the antitumor effects …

Are plant-based functional foods better choice against cancer than single phytochemicals? A critical review of current breast cancer research

A Kapinova, P Stefanicka, P Kubatka, P Zubor… - Biomedicine & …, 2017 - Elsevier
Breast cancer is the most common malignancy in women worldwide. Over 90% of all breast
cancer cases are of different 'sporadic'cell types, thus placing emphasis on the need for …

Effects and mechanisms of dietary bioactive compounds on breast cancer prevention

K Ganesan, B Du, J Chen - Pharmacological Research, 2022 - Elsevier
Breast cancer (BC) is the most often diagnosed cancer among females globally and has
become an increasing global health issue over the last decades. Despite the substantial …

New drugs from the sea: Pro-apoptotic activity of sponges and algae derived compounds

G Ercolano, P De Cicco, A Ianaro - Marine Drugs, 2019 - mdpi.com
Natural compounds derived from marine organisms exhibit a wide variety of biological
activities. Over the last decades, a great interest has been focused on the anti-tumour role of …

Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma

P Kubatka, M Kello, K Kajo, M Samec… - International Journal of …, 2020 - mdpi.com
Comprehensive scientific data provide evidence that isolated phytochemicals or whole plant
foods may beneficially modify carcinogenesis. The aim of this study was to evaluate the …

Antineoplastic effects of clove buds (Syzygium aromaticum L.) in the model of breast carcinoma

P Kubatka, S Uramova, M Kello, K Kajo… - Journal of Cellular …, 2017 - Wiley Online Library
It is supposed that plant functional foods, rich in phytochemicals, may potentially have
preventive effects in carcinogenesis. In this study, the anticancer effects of cloves in the in …

Chemopreventive and Therapeutic Efficacy of Cinnamomum zeylanicum L. Bark in Experimental Breast Carcinoma: Mechanistic In Vivo and In Vitro Analyses

P Kubatka, M Kello, K Kajo, M Samec, K Jasek… - Molecules, 2020 - mdpi.com
Comprehensive oncology research suggests an important role of phytochemicals or whole
plant foods in the modulation of signaling pathways associated with anticancer action. The …