Proteases play a crucial role in the progression and metastasis of ovarian cancer.
Pericellular protein degradation and fragmentation along with remodeling of the …

Recent studies indicate that cancer-associated fibroblasts (CAFs) are phenotypically and
functionally heterogeneous. However, little is known about CAF subtypes, the roles they play …

Inhibitors of poly (ADP-ribose) polymerase (PARP) and angiogenesis have demonstrated
single-agent activity in women with advanced ovarian cancer. Recent studies have aimed to …

Angiogenesis is one of the hallmarks of cancer and plays a crucial role in carcinogenesis
and progression of epithelial ovarian cancer. Antiangiogenic agent is the first approved …

Ovarian cancer is the most lethal gynecologic malignancy in the United States. Some
patients affected by ovarian cancers often present genome instability with one or more of the …

Ovarian cancer (OC) is one of the leading causes of female cancer death. Recent studies
have documented its extensive variations as a disease entity, in terms of cell or tissue of …

Simple Summary Aptamers are versatile molecules for cancer treatment. They can be used
to target specific molecules, conjugated to additional nucleic acid moieties or payloads. In …

Background In many malignancies including ovarian cancer, different angiogenic factors
have been related to poor prognosis. However, data on their relations to each other or …

Tumor angiogenesis is an essential process for growth and metastasis of cancer cells as it
supplies tumors with oxygen and nutrients. During tumor angiogenesis, many pro …

Ovarian cancer is a deadly malignancy with a growing therapeutic armamentarium, though
achieving sustained benefit in the clinic remains largely elusive. Through biomarker and …