Maternal ethanol consumption before paternal fertilization: Stimulation of hypocretin neurogenesis and ethanol intake in zebrafish offspring

AD Collier, SS Min, SD Campbell, MY Roberts… - Progress in Neuro …, 2020 - Elsevier
There are numerous clinical and pre-clinical studies showing that exposure of the embryo to
ethanol markedly affects neuronal development and stimulates alcohol drinking and related …

Long-term alterations in vulnerability to addiction to drugs of abuse and in brain gene expression after early life ethanol exposure

E Barbier, O Pierrefiche, D Vaudry, H Vaudry… - …, 2008 - Elsevier
Exposure to ethanol early in life can have long-lasting implications on brain function and
drug of abuse response later in life. The present study investigated in rats, the long-term …

Early exposure to environmental enrichment modulates the effects of prenatal ethanol exposure upon opioid gene expression and adolescent ethanol intake

A Wille-Bille, F Bellia, AMJ García… - …, 2020 - Elsevier
Prenatal ethanol exposure (PEE) promotes ethanol consumption in the adolescent offspring
accompanied by the transcriptional regulation of kappa opioid receptor (KOR) system …

Prevalence and patterns of prenatal alcohol exposure in Australian cohort and cross-sectional studies: a systematic review of data collection approaches

SL Young, SE Steane, NL Kent, N Reid… - International Journal of …, 2022 - mdpi.com
This study sought to determine data collection approaches in Australian cohort studies and
explore the potential impact on reported prenatal alcohol exposure (PAE) prevalence and …

Prenatal alcohol use: the role of lifetime problems with alcohol, drugs, depression, and violence

HA Flynn, ST Chermack - Journal of studies on alcohol and drugs, 2008 - jsad.com
Objective: The purpose of this study was to examine a broader array of lifetime factors that
theoretically may be associated with prenatal alcohol use than have previously been studied …

Fetal alcohol spectrum disorders: Zebrafish in the analysis of the milder and more prevalent form of the disease

D Seguin, R Gerlai - Behavioural brain research, 2018 - Elsevier
Abstract Fetal Alcohol Spectrum Disorders (FASD) represent a large unmet medical need.
Exposure of the developing human embryo to alcohol can lead to life-long suffering. Despite …

CB1R-mediated activation of caspase-3 causes epigenetic and neurobehavioral abnormalities in postnatal ethanol-exposed mice

S Subbanna, NN Nagre, M Shivakumar… - Frontiers in molecular …, 2018 - frontiersin.org
Alcohol exposure can affect brain development, leading to long-lasting behavioral problems,
including cognitive impairment, which together is defined as fetal alcohol spectrum disorder …

Effects of fetal substance exposure on offspring substance use

NC Dodge, JL Jacobson, SW Jacobson - Pediatric Clinics, 2019 - pediatric.theclinics.com
The National Institutes of Health have identified substance use disorders (SUDs) as a major
public health problem and noted that the prevalence of these disorders, which typically …

[HTML][HTML] Impact of the number of parents with alcohol use disorder on alcohol use disorder in offspring: a population-based study

G Yoon, J Westermeyer… - The Journal of …, 2013 - legacy.psychiatrist.com
Objective: Although parental alcohol use disorder (AUD) increases risk for alcohol problems
in offspring, no studies have evaluated the odds of AUD in offspring based on the number of …

Ethanol increases fetal human neurosphere size and alters adhesion molecule gene expression

SD Vangipuram, WE Grever, GC Parker… - Alcoholism: Clinical …, 2008 - Wiley Online Library
Background: Ethanol (ETOH) consumption by pregnant women can result in Fetal Alcohol
Spectrum Disorder (FASD). To date, the cellular targets and mechanisms responsible for …