Th17/Treg imbalance in COPD progression: A temporal analysis using a CS-induced model
Background The imbalance between pro-and anti-inflammatory immune responses plays a
pivotal role in chronic obstructive pulmonary disease (COPD) development and progression …
pivotal role in chronic obstructive pulmonary disease (COPD) development and progression …
Th17/Treg imbalance in COPD development: suppressors of cytokine signaling and signal transducers and activators of transcription proteins
LEF Silva, JD Lourenço, KR Silva, FPR Santana… - Scientific reports, 2020 - nature.com
Th17/Treg imbalance contributes to chronic obstructive pulmonary disease (COPD)
development and progression. However, intracellular signaling by suppressor of cytokine …
development and progression. However, intracellular signaling by suppressor of cytokine …
Restoring Th17/Treg balance via modulation of STAT3 and STAT5 activation contributes to the amelioration of chronic obstructive pulmonary disease by Bufei Yishen …
P Zhao, J Li, Y Tian, J Mao, X Liu, S Feng, J Li… - Journal of …, 2018 - Elsevier
Abstract Ethnopharmacology relevance Bufei Yishen formula (BYF), a Traditional Chinese
Medicine (TCM), has been extensively applied in clinical treatment of chronic obstructive …
Medicine (TCM), has been extensively applied in clinical treatment of chronic obstructive …
Haploinsufficiency of Hedgehog interacting protein causes increased emphysema induced by cigarette smoke through network rewiring
Background The HHIP gene, encoding Hedgehog interacting protein, has been implicated
in chronic obstructive pulmonary disease (COPD) by genome-wide association studies …
in chronic obstructive pulmonary disease (COPD) by genome-wide association studies …
Enhanced lung inflammatory response in whole-body compared to nose-only cigarette smoke-exposed mice
J Serré, AT Tanjeko, C Mathyssen… - Respiratory …, 2021 - Springer
Background Chronic obstructive pulmonary disease (COPD) is characterized by a
progressive and abnormal inflammatory response in the lungs, mainly caused by cigarette …
progressive and abnormal inflammatory response in the lungs, mainly caused by cigarette …
[HTML][HTML] Activation of C3a receptor is required in cigarette smoke-mediated emphysema
Exposure to cigarette smoke can initiate sterile inflammatory responses in the lung and
activate myeloid dendritic cells (mDCs) that induce differentiation of T helper type 1 (Th1) …
activate myeloid dendritic cells (mDCs) that induce differentiation of T helper type 1 (Th1) …
Cigarette smoke-induced inflammation: NLRP10-mediated mechanisms
Chronic obstructive pulmonary disease (COPD) is a progressive, life-threatening disease
that causes irreversible lung damage. Cigarette smoking is the chief etiologic factor for the …
that causes irreversible lung damage. Cigarette smoking is the chief etiologic factor for the …
Bufei Yishen Formula Restores Th17/Treg Balance and Attenuates Chronic Obstructive Pulmonary Disease via Activation of the Adenosine 2a Receptor
P Zhao, X Liu, H Dong, Y Tian, S Feng… - Frontiers in …, 2020 - frontiersin.org
Bufei Yishen formula (BYF) is a Traditional Chinese Medicine (TCM) reported to ameliorate
chronic obstructive pulmonary disease (COPD) by regulating the balance between T helper …
chronic obstructive pulmonary disease (COPD) by regulating the balance between T helper …
[HTML][HTML] Yu-Ping-Feng-San mitigates development of emphysema and its exacerbation induced by influenza virus in mice
L Deng, Y Chen, R Chen, S Qin, X Wu, S Liang… - Chinese Herbal …, 2024 - Elsevier
Abstract Objective Yu-Ping-Feng-San (YPFS) has been found to significantly reduce
exacerbation rate and the risk of a second exacerbation in patients with chronic obstructive …
exacerbation rate and the risk of a second exacerbation in patients with chronic obstructive …
Efferocytosis in lung mucosae: implications for health and disease
K Guimarães-Pinto, EP Maia, JRM Ferreira… - Immunology Letters, 2022 - Elsevier
Efferocytosis is imperative to maintain lung homeostasis and control inflammation.
Populations of lung macrophages are the main efferocytes in this tissue, responsible for …
Populations of lung macrophages are the main efferocytes in this tissue, responsible for …