Lung-on-a-chip platforms for modeling disease pathogenesis
A Dellaquila, EK Thomée, AH McMillan… - Organ-on-a-chip, 2020 - Elsevier
Much of our understanding of lung pathophysiology has been gained from traditional in vitro
and in vivo animal assays, but they are inadequate for investigating fundamental disease …
and in vivo animal assays, but they are inadequate for investigating fundamental disease …
[HTML][HTML] Psoralen attenuates cigarette smoke extract-induced inflammation by modulating CD8+ T lymphocyte recruitment and chemokines via the JAK2/STAT1 …
S Li, Q Li, W Chen, Y Zhong, J Sun, J Wu, Y Cao… - Heliyon, 2024 - cell.com
Chronic obstructive pulmonary disease (COPD) is a respiratory inflammatory disease.
Psoralen (PSO) is the main pharmacological component identified from Bu-Shen-Fang …
Psoralen (PSO) is the main pharmacological component identified from Bu-Shen-Fang …
[HTML][HTML] Severe reduction in number and function of peripheral T cells does not afford protection toward emphysema and bronchial remodeling induced in mice by …
G De Cunto, B Lunghi, B Bartalesi, E Cavarra… - The American Journal of …, 2016 - Elsevier
The protein Lck (p56 Lck) is a Src family tyrosine kinase expressed at all stages of thymocyte
development and is required for maturation of T cells. The targeted disruption of Lck gene in …
development and is required for maturation of T cells. The targeted disruption of Lck gene in …
A novel animal model of emphysema induced by anti-elastin autoimmunity
BH Gu, ML Sprouse, MC Madison, MJ Hong… - The Journal of …, 2019 - journals.aai.org
Loss of immune tolerance to self-antigens can promote chronic inflammation and disrupt the
normal function of multiple organs, including the lungs. Degradation of elastin, a highly …
normal function of multiple organs, including the lungs. Degradation of elastin, a highly …
Notch 信号通路在慢性阻塞性肺疾病免疫失衡中的作用及机制研究
杨鑫娜 - 2015 - ir.lzu.edu.cn
Objective We observed the influence of the Notch signaling pathway Notch1, Jagged1 and
Hes1 in COPD mouse model splenic-derived CD4+ T lymphocyte Th1, Th2, Th17, Treg …
Hes1 in COPD mouse model splenic-derived CD4+ T lymphocyte Th1, Th2, Th17, Treg …
比较加味过敏煎与玉屏风散对PM2. 5 致肺损伤大鼠的Thl7/Treg 细胞平衡的调节作用及机制
冯枫， 孟玉凤， 戴中， 郭昉… - Journal of Beijing …, 2020 - search.ebscohost.com
目的探讨加味过敏煎和玉屏风散通过调节辅助性T 细胞17 (Th17)/调节性T 细胞(Treg)
平衡干预PM2. 5 致肺损伤作用机制. 方法40 只SPF 级雄性Wistar 大鼠随机分为正常对照组 …
平衡干预PM2. 5 致肺损伤作用机制. 方法40 只SPF 级雄性Wistar 大鼠随机分为正常对照组 …
Characterization of biochemical, functional and structural changes in mice respiratory organs chronically exposed to cigarette smoke
H Tsuji, H Fujimoto, KM Lee, R Renne… - Inhalation …, 2015 - Taylor & Francis
Female C57BL/6 mice were exposed to mainstream cigarette smoke at 600 μg WTPM/L, 4
h/day and 5 days/week for up to 52 weeks. At 26, 52 and 65 weeks (52 weeks of exposure …
h/day and 5 days/week for up to 52 weeks. At 26, 52 and 65 weeks (52 weeks of exposure …
Immunology of chronic obstructive pulmonary disease and sulfur mustard induced airway injuries: implications for immunotherapeutic interventions
Y Panahi, F Jadidi-Niaragh… - Current …, 2016 - ingentaconnect.com
Background: Sulfur mustard (SM)-induced airway injuries and chronic obstructive pulmonary
disease (COPD) are characterized by chronic inflammation of the respiratory tract and share …
disease (COPD) are characterized by chronic inflammation of the respiratory tract and share …
[Retracted] Effect of Autoimmune Cell Therapy on Immune Cell Content in Patients with COPD: A Randomized Controlled Trial
W Li, G Li, W Zhou, H Wang… - … Mathematical Methods in …, 2022 - Wiley Online Library
Objective. To explore the effect of autoimmune cell therapy on immune cells in patients with
chronic obstructive pulmonary disease (COPD) and to provide a reference for clinical …
chronic obstructive pulmonary disease (COPD) and to provide a reference for clinical …