Cancer cells frequently display intrinsic or acquired resistance to chemically diverse
anticancer drugs, limiting therapeutic success. Among the main mechanisms of this …

Multiple drug resistance (MDR), referring to the resistance of cancer cells to a broad
spectrum of structurally and mechanistically unrelated drugs across membranes, severely …

The pharmacological characteristics of phytochemicals have prompted a lot of interest in
their application in disease management. Due to the high incidence of cancer related …

Cancer is a prominent cause of death globally. Currently, many drugs that are in clinical
practice are having a high prevalence of side effect and multidrug resistance. Risk of tumors …

ATP-binding cassette (ABC) transporters are involved in active pumping of many diverse
substrates through the cellular membrane. The transport mediated by these proteins …

The blood–brain barrier (BBB) has shown to be a significant obstacle to brain medication
delivery. The BBB in a healthy brain is a diffusion barrier that prevents most substances from …

Drug delivery systems have opened new avenues to improve the therapeutic effects of
already-efficient molecules. Particularly, Solid Lipid Nanoparticles (SLNs) have emerged as …

Introduction Fusarium graminearum is a most destructive fungal pathogen that causes
Fusarium head blight (FHB) disease in cereal crops, resulting in severe yield loss and …

Breast cancer has an extremely high incidence in women, and its morbidity and mortality
rank first among female tumors. With the increasing development of medicine today, the …

Anthelmintic resistance in human and animal pathogenic helminths has been spreading in
prevalence and severity. Multidrug resistance is a widespread problem in livestock animals …