[HTML][HTML] Exploring cerebral amyloid angiopathy: Insights into pathogenesis, diagnosis, and treatment

M Cozza, L Amadori, V Boccardi - Journal of the Neurological Sciences, 2023 - Elsevier
Abstract Cerebral Amyloid Angiopathy (CAA) is a neurological disorder characterized by the
deposition of amyloid plaques in the walls of cerebral blood vessels. This condition poses …

Transporter regulation in critical protective barriers: focus on brain and placenta

V Taggi, M Riera Romo, M Piquette-Miller… - Pharmaceutics, 2022 - mdpi.com
Drug transporters play an important role in the maintenance of chemical balance and
homeostasis in different tissues. In addition to their physiological functions, they are crucial …

Cerebrospinal fluid biomarkers for cerebral amyloid angiopathy

JA Sembill, C Lusse, M Linnerbauer… - Brain …, 2023 - academic.oup.com
Integrating cerebrospinal fluid-biomarkers into diagnostic workup of patients with sporadic
cerebral amyloid angiopathy may support early and correct identification. We aimed to …

Comparative methods for quantifying plasma biomarkers in Alzheimer's disease: implications for the next frontier in cerebral amyloid angiopathy diagnostics

RT Muir, Z Ismail, SE Black, EE Smith - Alzheimer's & Dementia, 2024 - Wiley Online Library
Plasma amyloid beta (Aβ) and tau are emerging as accessible biomarkers for Alzheimer's
disease (AD). However, many assays exist with variable test performances, highlighting the …

Clinical characteristics, neuroimaging markers, and outcomes in patients with cerebral amyloid angiopathy: a prospective cohort study

A Theodorou, L Palaiodimou… - Journal of Clinical …, 2023 - mdpi.com
Background and purpose: Sporadic cerebral amyloid angiopathy (CAA) is a small vessel
disease, resulting from progressive amyloid-β deposition in the media/adventitia of cortical …

Magnetic Resonance Imaging-Negative Cerebral Amyloid Angiopathy: Cerebrospinal Fluid Amyloid-β42 over Amyloid Positron Emission Tomography

JM Pyun, MJ Kang, SJ Baek, K Lee, YH Park… - The Journal of …, 2024 - Springer
Background Cerebral amyloid angiopathy (CAA) pathology is becoming increasingly
important in Alzheimer's disease (AD) because of its potential link to amyloid-related …

Fluid biomarkers in cerebral amyloid angiopathy

SM Savar, B Ma, E Hone, F Jahan, S Markovic… - Frontiers in …, 2024 - frontiersin.org
Cerebral amyloid angiopathy (CAA) is a type of cerebrovascular disorder characterised by
the accumulation of amyloid within the leptomeninges and small/medium-sized cerebral …

Profiling amyloid‐β peptides as biomarkers for cerebral amyloid angiopathy

E van den Berg, I Kersten, G Brinkmalm… - Journal of …, 2024 - Wiley Online Library
Brain amyloid‐β (Aβ) deposits are key pathological hallmarks of both cerebral amyloid
angiopathy (CAA) and Alzheimer's disease (AD). Microvascular deposits in CAA mainly …

CSF and plasma biomarkers in cerebral amyloid angiopathy: A single-center study and a systematic review/meta-analysis

A Theodorou, I Tsantzali, MI Stefanou… - European Stroke …, 2024 - journals.sagepub.com
Introduction: There are limited data regarding cerebrospinal fluid (CSF) and plasma
biomarkers among patients with Cerebral Amyloid Angiopathy (CAA). We sought to …

Anti-Amyloid Therapy, AD, and ARIA: Untangling the Role of CAA

MK Sin, E Zamrini, A Ahmed, K Nho… - Journal of Clinical …, 2023 - mdpi.com
Anti-amyloid therapies (AATs), such as anti-amyloid monoclonal antibodies, are emerging
treatments for people with early Alzheimer's disease (AD). AATs target amyloid β plaques in …