Glutamate and GABA in microglia-neuron cross-talk in Alzheimer's disease
GA Czapski, JB Strosznajder - International Journal of Molecular Sciences, 2021 - mdpi.com
The physiological balance between excitation and inhibition in the brain is significantly
affected in Alzheimer's disease (AD). Several neuroactive compounds and their signaling …
affected in Alzheimer's disease (AD). Several neuroactive compounds and their signaling …
The role of gut microbiota in pathogenesis of Alzheimer's disease
M Bostanciklioğlu - Journal of applied microbiology, 2019 - academic.oup.com
This paper describes the effects of the gut microbiota on the pathogenesis of Alzheimer's
pathology by evaluating the current original key findings and identifying gaps in the …
pathology by evaluating the current original key findings and identifying gaps in the …
[HTML][HTML] Transformative network modeling of multi-omics data reveals detailed circuits, key regulators, and potential therapeutics for Alzheimer's disease
To identify the molecular mechanisms and novel therapeutic targets of late-onset
Alzheimer's Disease (LOAD), we performed an integrative network analysis of multi-omics …
Alzheimer's Disease (LOAD), we performed an integrative network analysis of multi-omics …
Benzodiazepines in Alzheimer's disease: beneficial or detrimental effects
Dementia is considered a clinical syndrome characterized by cognitive dysfunction and
memory loss. Alzheimer's disease (AD) is the most common type of dementia. AD is linked …
memory loss. Alzheimer's disease (AD) is the most common type of dementia. AD is linked …
The GABAergic system as a therapeutic target for Alzheimer's disease
B Calvo‐Flores Guzmán, C Vinnakota… - Journal of …, 2018 - Wiley Online Library
Glutamatergic and cholinergic dysfunction are well‐attested features of Alzheimer's disease
(AD), progressing with other pathological indices of the disorder and exacerbating neuronal …
(AD), progressing with other pathological indices of the disorder and exacerbating neuronal …
Intranasal delivery of pro-resolving lipid mediators rescues memory and gamma oscillation impairment in AppNL-GF/NL-GF mice
C Emre, LE Arroyo-García, KV Do, B Jun… - Communications …, 2022 - nature.com
Sustained microglial activation and increased pro-inflammatory signalling cause chronic
inflammation and neuronal damage in Alzheimer's disease (AD). Resolution of inflammation …
inflammation and neuronal damage in Alzheimer's disease (AD). Resolution of inflammation …
Functional excitatory to inhibitory synaptic imbalance and loss of cognitive performance in people with Alzheimer's disease neuropathologic change
Individuals at distinct stages of Alzheimer's disease (AD) show abnormal
electroencephalographic activity, which has been linked to network hyperexcitability and …
electroencephalographic activity, which has been linked to network hyperexcitability and …
Unsupervised excitation: GABAergic dysfunctions in Alzheimer's disease
EA Giovannetti, M Fuhrmann - Brain research, 2019 - Elsevier
Alzheimer's disease (AD) is characterized by the classical hallmarks of Aβ-deposition and
tau-pathology that are thought to ultimately lead to synapse and neuron loss. Although long …
tau-pathology that are thought to ultimately lead to synapse and neuron loss. Although long …
Insights on benzodiazepines' potential in Alzheimer's disease
Alzheimer's disease (AD) is the most frequent type of dementia characterized by the
deposition of amyloid beta (Aβ) plaque and tau-neurofibrillary tangles (TNTs) in the brain …
deposition of amyloid beta (Aβ) plaque and tau-neurofibrillary tangles (TNTs) in the brain …
Sensory processing deficits and related cortical pathological changes in Alzheimer's disease
Alzheimer's disease (AD) is a progressive neurodegenerative disorder primarily affecting
cognitive functions. However, sensory deficits in AD start to draw attention due to their high …
cognitive functions. However, sensory deficits in AD start to draw attention due to their high …