Several curcuminoids have been identified from rhizome of the common spice Curcuma
longa (Zingaberaceae) and related plant species. Curcuminoids are known to display …

The increasing prevalence of hypertension, owing to modern lifestyles and the increasing
elderly population, is contributing to the global burden of cardiovascular (CV) disease …

Hypertension is one of the most important and widespread risk factors for the development
of cardiovascular disease. Once, combination therapy was traditionally reserved as a third …

As combinations of drugs from different classes that have synergistic or additive effect and
properties to cancel out each others' untoward hemodynamic and metabolic effects become …

High blood pressure (BP) is the major cardiovascular risk factor and the main cause of death
around the world. Control of blood pressure reduces the high mortality associated with …

The purpose of this study was to compare the combination treatments of manidipine/delapril
and olmesartan/hydrochlorothiazide (HCTZ) in elderly diabetic hypertensives. After a 4 …

Hypertensive heart disease was difficult to cure with drugs, and most patients had poor
compliance, leading to recurrent disease and poor quality of life. The intelligent …

Current estimates (1) reveal that more than a quarter of the adult world population has
hypertension. An approximate one billion of people with diagnosed and undiagnosed …

A simple, specific, fast and sensitive liquid chromatography–tandem mass spectrometry (LC-
MS/MS) method for the simultaneous analysis of delapril (DEL) and manidipine (MAN) from …

Abstract▴ Delapril/manidipine 30mg/10mg is a new oral, once-daily, fixed combination of an
ACE inhibitor and a dihydropyridine calcium-channel antagonist for the treatment of …