The role of endocrine disruptors (EDs) in the human prostate gland is an overlooked issue
even though the prostate is essential for male fertility. From experimental models, it is known …

Progesterone (PRG) is a key cyclical reproductive hormone that has a significant impact on
female organs in vertebrates. It is mainly produced by the corpus luteum of the ovaries, but …

We have previously demonstrated that RACK1, which expression is under steroid hormone
control, plays an important role in the activation of immune cells and its expression can be …

The existence of a complex hormonal balance among glucocorticoids, androgens and
estrogens involved in the regulation of Receptor for Activated C Kinase 1 (RACK1) …

Most kinase inhibitors are designed to bind to highly homologous ATP-binding sites, which
leads to promiscuity and possible off-target effects. Allostery is an alternative approach to …

Humans can be exposed to endocrine disruptors (EDs) in numerous ways. EDs can interfere
with endogenous hormones at different levels, resulting in numerous adverse human health …

Head and neck squamous cell carcinoma (HNSCC), the most prevalent cancer in the head
and neck region, develops from the mucosal epithelium of the upper aerodigestive tract. Its …

Estrogens and their role in cancer are well-studied, and some cancer types are classified in
terms of their response to them. In recent years, a G protein-coupled estrogen receptor …

Diabetes mellitus (DM) is a chronic metabolic condition characterized predominantly by
hyperglycemia. The most common causes contributing to the pathophysiology of diabetes …

The role of protein misfolding, deposition, and clearance has been the dominant topic in the
last decades of investigation in the field of neurodegeneration. The impairment of protein …