[PDF][PDF] Oyster As, Cd, Cu, Hg, Pb and Zn Levels in the Northern South China Sea: Long-term Spatiotemporal Distributions, Interacting Effects, and Risk Assessment to …

L Wang, X Wang, H Chen, Z Wang, X Jia - 2021 - scholar.archive.org
Estuarine and coastal ecosystems are often considered vulnerable due to the complex
biogeochemical processes and 14 the human disturbances through a variety of pollution …

Oestrogen receptor-independent actions of oestrogen in cancer

P Gopinath, RP Oviya, G Gopisetty - Molecular Biology Reports, 2023 - Springer
Oestrogen, the primary female sex hormone, plays a significant role in tumourigenesis. The
major pathway for oestrogen is via binding to its receptor [oestrogen receptor (ERα or β)] …

Metal-organic frameworks for hepatocellular carcinoma therapy and mechanism

Y Feng, W Wu, M Li - Frontiers in Pharmacology, 2022 - frontiersin.org
In recent years, metal organic frameworks (MOFs) have attracted increasing attention in
cancer therapy, because they can enhance the anticancer efficacy of photodynamic therapy …

CK-3, a novel methsulfonyl pyridine derivative, suppresses hepatocellular carcinoma proliferation and invasion by blocking the PI3K/AKT/mTOR and MAPK/ERK …

Q Wu, T Liu, B Hu, X Li, Y Wu, X Sun, X Jiang… - Frontiers in …, 2021 - frontiersin.org
Hepatocellular carcinoma (HCC) is an aggressive tumor with a poor prognosis that highly
expresses phosphatidylinositol 3-kinase (PI3K) and mitogen-activated protein kinase (ERK) …

G6PD and machine learning algorithms as prognostic and diagnostic indicators of liver hepatocellular carcinoma

F Li, B Wang, H Li, L Kong, B Zhu - BMC cancer, 2024 - Springer
Abstract Background Liver Hepatocellular carcinoma (LIHC) exhibits a high incidence of
liver cancer with escalating mortality rates over time. Despite this, the underlying pathogenic …

2-methoxyestradiol inhibits melanoma cell growth by activating adaptive immunity

W Hua, X Huang, J Li, W Feng, Y Sun… - Immunopharmacology …, 2022 - Taylor & Francis
Background: The overall survival of melanoma patients remains poor despite advancements
in surgical treatment and targeted therapies. Therefore, there is a need to develop new …

Preparation of 2-methoxyestradiol self-emulsified drug delivery system and the effect on combination therapy with doxorubicin against MCF-7/ADM cells

C Yu, C Li, H Pan, T Li, S He - AAPS PharmSciTech, 2022 - Springer
Due to the poor solubility and bioavailability of 2-methoxyestradiol (2-ME), 2-ME emulsified
drug delivery system (2-ME-SEDDS) was designed and characterized. After dilution with 5 …

PLAGL2 promotes the stemness and is upregulated by transcription factor E2F1 in human lung cancer

Y Lin, P Lin, W Guo, J Huang, X Xu… - Environmental …, 2023 - Wiley Online Library
This study mainly focuses on revealing the role of PLAGL2 in lung cancer stemness. In vitro
and in vivo experiments were performed to evaluate the effects of PLAGL2 on lung cancer …

Co-amorphous mixture of erlotinib hydrochloride and gallic acid for enhanced antitumor effects

X Wang, J Cao, Z Li, R Xu, Y Guo, F Pu, X Xiao… - Journal of Drug Delivery …, 2024 - Elsevier
Erlotinib hydrochloride (ERL) is a frontline drug approved by FDA for the treatment of several
types of cancers, while its clinical application is seriously compromised by poor water …

Colorectal cancer subtyping and prognostic model construction based on interleukin-related genes

J Song, J Chen, Y Chen, Y Wang… - Physiological …, 2024 - journals.physiology.org
Members of the interleukin (IL) family are closely linked to cancer development and
progression. However, research on the prognosis of colorectal cancer (CRC) related to IL is …