Neutrophils are one of the most important effector cells of the innate immune response (1).
They are traditionally seen as a homogenous population of short‐lived cells mainly involved …

We review the morphofunctional characteristics of CD34+ stromal fibroblastic/fibrocytic cells
(CD34+ SFCs) and report our observations. We consider the following aspects of CD34+ …

The Eph/ephrin receptor–ligand system plays an important role in embryogenesis and adult
life, principally by influencing cell behavior through signaling pathways, resulting in …

Endothelial-immune cell cross-talk goes well beyond leukocyte and lymphocyte trafficking,
since immune cells are able to intimately regulate vessel formation and function. Here we …

Introduction• The importance of angiogenesis in physiological and pathological conditions•
The contribution of immune cells to angiogenesis in inflammation and tumour growth• …

Type I interferons (IFNs) were first characterized in the process of viral interference.
However, since then, IFNs are found to be involved in a wide range of biological processes …

Eph receptor tyrosine kinases and their Ephrin ligands represent an important signaling
system with widespread roles in cell physiology and disease. Receptors and ligands in this …

Harnessing neutrophils for the eradication of cancer cells remains an attractive but still
controversial notion. In this study, we provide evidence that neutrophils are required to …

Recombinant tissue plasminogen activator (t-PA), the only approved stroke treatment, is
used for clot lysis within the occluded brain artery. Unfortunately, matrix metalloproteinase-9 …

Polymorphonuclear neutrophils (PMN) are key components of the innate immunity and their
efficient recruitment to the sites of lesion is a prerequisite for acute inflammation. Signaling …