Liposomes are well-recognized and essential nano-sized drug delivery systems. Liposomes
are phospholipid vesicles comprised of cell membrane components and have been …

Today, liposomes are among the most applied technologies for the encapsulation and
delivery of bioactive agents and many different compounds in biological, pharmaceutical …

RNA interference (RNAi) has become the method of choice to suppress gene expression in
vitro. It is also emerging as a powerful tool for in vivo research with over 90 studies …

Toll-like receptors (TLR) are an emerging family of receptors that recognize pathogen-
associated molecular patterns and promote the activation of leukocytes and intrinsic renal …

Antisense oligonucleotides have the potential to make revolutionary contributions to basic
science and medicine. Oligonucleotides can bind mRNA and inhibit translation. Because …

Purpose: The use of the CD20-specific antibody rituximab has greatly improved the
response to treatment of CD20+ follicular lymphoma. Despite the success of rituximab …

The design of the drug delivery depends upon different parameters. One of the most
noticeable factors in design of the drug delivery is drug-release profile which determines the …

Synthetic oligodeoxynucleotides (ODN) containing unmethylated CpG motifs act as immune
adjuvants in mice, boosting the humoral and cellular response to coadministered Ags. CpG …

Intestinal inflammation in inflammatory bowel disease (IBD) and experimental models of
colitis is characterized by a dysregulated intestinal immune response with elevated levels of …

Allergen immunotherapy is an effective but underutilized treatment for atopic asthma. We
have previously demonstrated that CpG oligodeoxynucleotides (CpG ODN) can prevent the …