Natural Product-Inspired Dopamine Receptor Ligands
M Dorogan, HK Namballa… - Journal of Medicinal …, 2024 - ACS Publications
Due to their evolutionary bias as ligands for biologically relevant drug targets, natural
products offer a unique opportunity as lead compounds in drug discovery. Given the …
products offer a unique opportunity as lead compounds in drug discovery. Given the …
Preparation and characterization of bionics Oleosomes with high loading efficiency: The enhancement of hydrophobic space and the effect of cholesterol
Liposomes (LIP) loaded with natural active ingredients have significant potential in the food
industry. However, their low loading efficiency (LE) hampers the advancement of liposomal …
industry. However, their low loading efficiency (LE) hampers the advancement of liposomal …
DFT calculations, molecular docking, binding free energy analysis and cytotoxicity assay of 7, 7-dimethylaporphine alkaloids with methylenedioxy ring in positions 1 …
ADS Branches, JN da Silva, MDL de Oliveira… - Computational and …, 2024 - Elsevier
In this paper, we present a comprehensive characterization of three 7, 7-dimethylaporphine
alkaloids at a molecular quantum mechanical level using Density Functional Theory (DFT) …
alkaloids at a molecular quantum mechanical level using Density Functional Theory (DFT) …
Identification of the cytochrome P450s responsible for the biosynthesis of two types of aporphine alkaloids and their de novo biosynthesis in yeast
Q Li, X Jiao, X Li, W Shi, Y Ma, X Tan… - Journal of Integrative …, 2024 - Wiley Online Library
Aporphine alkaloids have diverse pharmacological activities; however, our understanding of
their biosynthesis is relatively limited. Previous studies have classified aporphine alkaloids …
their biosynthesis is relatively limited. Previous studies have classified aporphine alkaloids …
Understanding the Impact of the Methylenedioxy Ring on the Structure, Spectroscopic Properties, and Bioactivity of 7, 7-Dimethyl Aporphine Alkaloids
ADS Branches, JN da Silva, MD L de Oliveira… - Micael Davi and … - papers.ssrn.com
In this paper, we present a comprehensive characterization of two 7, 7-dimethylaporphine
alkaloids at the molecular quantum mechanical level using density functional theory (DFT) …
alkaloids at the molecular quantum mechanical level using density functional theory (DFT) …