microRNAs biogenesis, functions and role in tumor angiogenesis

T Annese, R Tamma, M De Giorgis, D Ribatti - Frontiers in oncology, 2020 - frontiersin.org
microRNAs (miRNAs) are small non-coding RNA molecules, evolutionary conserved. They
target more than one mRNAs, thus influencing multiple molecular pathways, but also …

The non-canonical aspects of microRNAs: many roads to gene regulation

CJ Stavast, SJ Erkeland - Cells, 2019 - mdpi.com
MicroRNAs (miRNAs) are critical regulators of gene expression. As miRNAs are frequently
deregulated in many human diseases, including cancer and immunological disorders, it is …

The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles

AM Leidal, HH Huang, T Marsh, T Solvik, D Zhang… - Nature cell …, 2020 - nature.com
Traditionally viewed as an autodigestive pathway, autophagy also facilitates cellular
secretion; however, the mechanisms underlying these processes remain unclear. Here, we …

Emerging functions for snoRNAs and snoRNA-derived fragments

M Wajahat, CP Bracken, A Orang - International journal of molecular …, 2021 - mdpi.com
The widespread implementation of mass sequencing has revealed a diverse landscape of
small RNAs derived from larger precursors. Whilst many of these are likely to be byproducts …

Interaction and cross-talk between non-coding RNAs

S Yamamura, M Imai-Sumida, Y Tanaka… - Cellular and molecular …, 2018 - Springer
Non-coding RNA (ncRNA) has been shown to regulate diverse cellular processes and
functions through controlling gene expression. Long non-coding RNAs (lncRNAs) act as a …

Small nucleolar RNAs tell a different tale

J Kufel, P Grzechnik - Trends in Genetics, 2019 - cell.com
Transcribing RNA Polymerase II interacts with multiple factors that orchestrate maturation
and stabilisation of messenger RNA. For the majority of noncoding RNAs, the polymerase …

An updated human snoRNAome

H Jorjani, S Kehr, DJ Jedlinski, R Gumienny… - Nucleic acids …, 2016 - academic.oup.com
Small nucleolar RNAs (snoRNAs) are a class of non-coding RNAs that guide the post-
transcriptional processing of other non-coding RNAs (mostly ribosomal RNAs), but have …

RNAcentral: a comprehensive database of non-coding RNA sequences

Nucleic acids research, 2017 - academic.oup.com
RNAcentral is a database of non-coding RNA (ncRNA) sequences that aggregates data
from specialised ncRNA resources and provides a single entry point for accessing ncRNA …

Principles and innovative technologies for decrypting noncoding RNAs: from discovery and functional prediction to clinical application

YM Sun, YQ Chen - Journal of hematology & oncology, 2020 - Springer
Noncoding RNAs (ncRNAs) are a large segment of the transcriptome that do not have
apparent protein-coding roles, but they have been verified to play important roles in diverse …

Dual function of C/D box small nucleolar RNAs in rRNA modification and alternative pre-mRNA splicing

M Falaleeva, A Pages, Z Matuszek… - Proceedings of the …, 2016 - National Acad Sciences
C/D box small nucleolar RNAs (SNORDs) are small noncoding RNAs, and their best-
understood function is to target the methyltransferase fibrillarin to rRNA (for example …