Mammals have two specialized vascular circulatory systems: the blood vasculature and the
lymphatic vasculature. The lymphatic vasculature is a unidirectional conduit that returns …

The lymphatic system serves an integral role in fluid homeostasis, lipid metabolism and
immune control. In cancer, the lymph nodes that drain solid tumours are a primary site of …

We investigated the relationship between gut health, visceral fat dysfunction and metabolic
disorders in diet-induced obesity. C57BL/6J mice were fed control or high saturated fat diet …

Resolution of acute inflammation is an active process essential for appropriate host
responses, tissue protection and the return to homeostasis,,. During resolution, specific …

Obesity, defined as excess fat mass, increases risks for multiple metabolic diseases, such as
type 2 diabetes, cardiovascular disease and several types of cancer. Over and above fat …

Obesity increases morbidity and mortality through its multiple effects on nearly every human
system. However, the various aspects of the association between obesity and infection have …

Ageing, like obesity, is often associated with alterations in metabolic and inflammatory
processes resulting in morbidity from diseases characterised by poor metabolic control …

The world is now experiencing an epidemic of obesity. Although the effects of obesity on the
development of metabolic and cardiovascular problems are well studied, much less is …

Obesity is a key risk factor for metabolic and cardiovascular diseases, and although we
understand the mechanisms regulating weight and energy balance, the causes of some …

Childhood obesity is a leading public health problem worldwide, as it is increasingly
prevalent and therefore responsible for serious obesity-related comorbidities, not only in …