[HTML][HTML] Functional hydrogels for the treatment of myocardial infarction

T Wu, W Liu - NPG Asia Materials, 2022 - nature.com
Myocardial infarction (MI) is a major disease posing a significant threat to human health, as it
leads to necrosis of numerous cardiomyocytes (CMs), left ventricle dilation, and cardiac …

[HTML][HTML] Stimuli-responsive hydrogels: Smart state of-the-art platforms for cardiac tissue engineering

HM El-Husseiny, EA Mady, WA El-Dakroury… - … in Bioengineering and …, 2023 - frontiersin.org
Biomedicine and tissue regeneration have made significant advancements recently,
positively affecting the whole healthcare spectrum. This opened the way for them to develop …

[HTML][HTML] Wet adhesive hydrogel cardiac patch loaded with anti-oxidative, autophagy-regulating molecule capsules and MSCs for restoring infarcted myocardium

T Wu, X Zhang, Y Liu, C Cui, Y Sun, W Liu - Bioactive Materials, 2023 - Elsevier
Hydrogel patch-based stem cell transplantation and microenvironment-regulating drug
delivery strategy is promising for the treatment of myocardial infarction (MI). However, the …

[HTML][HTML] An injectable conductive hydrogel with dual responsive release of rosmarinic acid improves cardiac function and promotes repair after myocardial infarction

L Zhang, Z Bei, T Li, Z Qian - Bioactive Materials, 2023 - Elsevier
Myocardial infarction (MI) causes irreversible damage to the heart muscle, seriously
threatening the lives of patients. Injectable hydrogels have attracted extensive attention in …

Frozen reinforced microneedles loaded with NIR-photothermal nanozyme for keratitis treatment

B Kong, R Liu, J Shan, M Li, X Zhou, Y Zhao - Nano Today, 2023 - Elsevier
Developing a potential alternative with safe, minimally invasive, and highly effective
antimicrobial properties is significant for treating bacterial keratitis. In this paper, we present …

Cornea‐Inspired ultrasound‐responsive adhesive hydrogel patches for keratitis treatment

B Kong, R Liu, X Hu, M Li, X Zhou… - Advanced Functional …, 2024 - Wiley Online Library
Biomedical patches offer significant potential for keratitis treatment. Building on advances in
multifunctionality and biomimicry, an innovative, multifunctional hydrogel patch with high …

An injectable mitochondria-targeted nanodrug loaded-hydrogel for restoring mitochondrial function and hierarchically attenuating oxidative stress to reduce …

X Zhang, Y Sun, R Yang, B Liu, Y Liu, J Yang, W Liu - Biomaterials, 2022 - Elsevier
Timely reperfusion is the common treatment for myocardial infarction. However, ischemia-
reperfusion (I/R) therapy can lead to oxidative stress and mitochondrial dysfunction that …

Extracellular matrix/glycopeptide hybrid hydrogel as an immunomodulatory niche for endogenous cardiac repair after myocardial infarction

P Kong, J Dong, W Li, Z Li, R Gao, X Liu… - Advanced …, 2023 - Wiley Online Library
The treatment of myocardial infarction (MI) remains a substantial challenge due to excessive
inflammation, massive cell death, and restricted regenerative potential, leading to …

Chinese herb-crosslinked hydrogel bearing rBMSCs-laden polyzwitterion microgels: self-adaptive manipulation of micromilieu and stemness maintenance for …

Y Liu, X Zhang, T Wu, B Liu, J Yang, W Liu - Nano Today, 2021 - Elsevier
Injectable hydrogels and stem cells have been increasingly applied to treat myocardial
infarction (MI). However, the harsh microenvironment adversely affects the survival of …

YAP‐Suppressive Nanodrug Crosslinked Self‐Immunoregulatory Polysaccharide Injectable Hydrogel for Attenuating Cardiac Fibrosis to Treat Myocardial Infarction

Y Sun, X Zhang, T Wu, Z Zhang… - Advanced Functional …, 2023 - Wiley Online Library
The cardiac fibrosis caused by excessive deposition of collagen and the fibro‐inflammatory
cascade reaction severely impedes the cardiac regenerative efficiency after myocardial …