Members of the nucleotide-binding domain and leucine-rich repeat (LRR)-containing (NLR)
family and the pyrin and HIN domain (PYHIN) family can form multiprotein complexes …

The innate immune system includes several classes of pattern recognition receptors (PRRs),
including membrane-bound Toll-like receptors (TLRs) and nucleotide-binding …

The plant immune system involves cell-surface receptors that detect intercellular pathogen-
derived molecules, and intracellular receptors that activate immunity upon detection of …

INTRODUCTION The inflammasomes and the complement system are traditionally viewed
as quintessential components of innate immunity required for the detection and elimination …

The NLRP3 inflammasome has a fundamental role in host defence against microbial
pathogens and its deregulation may cause diverse inflammatory diseases. NLRP3 protein …

The inflammasome regulates innate immunity by serving as a signaling platform. The Nod‑
like receptor protein 3 (NLRP3) inflammasome, equipped with NLRP3, the adaptor protein …

Although much progress is being made in understanding the molecular pathways in the
placenta that are involved in the pathophysiology of pregnancy-related disorders, a …

The extensive existing of microplastics (MPs) in the ecosystem have increased considerable
attention concerning their potential adverse effects, the toxicities and the underlying …

The NLRP3 (NLR family pyrin domain containing 3) inflammasome is involved in diverse
inflammatory diseases, thus strict control of its activation is necessary to prevent excessive …

Aims: The NLRP3 inflammasome is a multiprotein complex that protects hosts against a
variety of pathogens. However, the molecular mechanisms of modulating NLRP3 …