Role of neurogenic inflammation in local communication in the visceral mucosa

LA Birder, FA Kullmann - Seminars in immunopathology, 2018 - Springer
Intense research has focused on the involvement of the nervous system in regard to cellular
mechanisms underlying neurogenic inflammation in the pelvic viscera. Evidence supports …

Transient receptor potential channels in bladder function

A Avelino, A Charrua, B Frias, C Cruz… - Acta …, 2013 - Wiley Online Library
The transient receptor potential (TRP) superfamily of cationic ion channels includes proteins
involved in the transduction of several physical and chemical stimuli to finely tune …

[HTML][HTML] Astaxanthin alleviates neuropathic pain by inhibiting the MAPKs and NF-κB pathways

L Zhao, X Tao, T Song - European Journal of Pharmacology, 2021 - Elsevier
Neuropathic pain is a complex condition that usually lasts a lifetime and has a major
negative impact on life after injury. Improving pain management is an important and unmet …

Increase in blood levels of growth factors involved in the neuroplasticity process by using an extremely low frequency electromagnetic field in post-stroke patients

N Cichoń, M Bijak, P Czarny, E Miller… - Frontiers in Aging …, 2018 - frontiersin.org
Background: Neuroplasticity ensures the improvement of functional status in patients after
stroke. The aim of this study was to evaluate the effect of extremely low-frequency …

Down regulation of vascular endothelial growth factor is associated with decreased inflammation after intravesical OnabotulinumtoxinA injections combined with …

CH Peng, JF Jhang, JH Shie, HC Kuo - Urology, 2013 - Elsevier
Objective To measure the expression of vascular endothelial growth factor (VEGF) in
bladder tissue and improvement of clinical symptoms and inflammatory biomarkers after …

[HTML][HTML] SETD6 regulates NF-κB signaling in urothelial cell survival: Implications for bladder cancer

N Mukherjee, E Cardenas, R Bedolla, R Ghosh - Oncotarget, 2017 - ncbi.nlm.nih.gov
Non-muscle invasive bladder cancer has a high recurrence rate of 45-70%, progressing to
muscle invasive disease in about 15% of those patients over a 5-year period. Administration …

Platelet-rich plasma attenuates the UPEC-induced cystitis via inhibiting MMP-2, 9 activities and downregulation of NGF and VEGF in Canis Lupus Familiaris model

AI Abdelgalil, AM Yassin, MS Khattab, EA Abdelnaby… - Scientific Reports, 2024 - nature.com
One of the most prevalent disorders of the urinary system is urinary tract infection, which is
mostly brought on by uropathogenic Escherichia coli (UPEC). The objective of this study was …

[HTML][HTML] Angiogenic factors, bladder neuroplasticity and interstitial cystitis—new pathobiological insights

R Saban - Translational andrology and urology, 2015 - ncbi.nlm.nih.gov
Vascular endothelial growth factor (VEGF) is essential for normal embryonic development,
and maintenance of adult vascular function. Originally described as a vascular permeability …

Functional effects of blocking VEGF/VEGFR2 signaling in the rat urinary bladder in acute and chronic CYP-induced cystitis

K Tooke, B Girard, MA Vizzard - American Journal of …, 2019 - journals.physiology.org
High expression of VEGF is associated with immature angiogenesis within the urinary
bladder wall and bladder afferent nerve sensitization, leading to visceral hyperalgesia and …

Anti‐vascular endothelial growth factor treatment decreases bladder pain in cyclophosphamide cystitis: a Multidisciplinary Approach to the Study of Chronic Pelvic …

HH Lai, B Shen, P Vijairania, X Zhang… - BJU …, 2017 - Wiley Online Library
Objective To investigate whether treatment with anti‐vascular endothelial growth factor
(VEGF)‐neutralizing antibodies can reduce pain and voiding dysfunction in the …