Research advances of engineered exosomes as drug delivery carrier

L Huang, E Wu, J Liao, Z Wei, J Wang, Z Chen - ACS omega, 2023 - ACS Publications
Exosomes are nanoscale vesicles secreted by living cells that have similar membrane
composition to parental cells and carry a variety of proteins, lipids, and nucleic acids …

Therapeutic potential of RNA-enriched extracellular vesicles: the next generation in RNA delivery via biogenic nanoparticles

M Muskan, P Abeysinghe, R Cecchin, H Branscome… - Molecular Therapy, 2024 - cell.com
Exosomes are extracellular vesicles (EVs)(∼ 50–150 nm) that have emerged as promising
vehicles for therapeutic applications and drug delivery. These membrane-bound particles …

Therapeutic applications of extracellular vesicles in inflammatory bowel disease

SH Kim, B Keum, S Kwak, J Byun, JM Shin… - International journal of …, 2024 - mdpi.com
The treatment landscape for inflammatory bowel disease (IBD) has undergone substantial
advancements with the introduction of biologics. However, a considerable number of …

Human Probiotic Lactobacillus paracasei-Derived Extracellular Vesicles Improve Tumor Necrosis Factor-α-Induced Inflammatory Phenotypes in Human Skin

KS Lee, Y Kim, JH Lee, S Shon, A Kim, AVQ Pham… - Cells, 2023 - mdpi.com
Lactic acid bacteria (LAB), a probiotic, provide various health benefits. We recently isolated
a new Lactobacillus paracasei strain with strong anti-inflammatory effects under …

A vivid outline demonstrating the benefits of exosome-mediated drug delivery in CNS-associated disease environments

R Ray, SG Chowdhury, P Karmakar - Archives of Biochemistry and …, 2024 - Elsevier
The efficacy of drug delivery mechanisms has been improvised with time for different
therapeutic purposes. In most cases, nano-sized delivery systems have been modeled over …

Insight into the Functional Dynamics and Challenges of Exosomes in Pharmaceutical Innovation and Precision Medicine

A Sharma, A Yadav, A Nandy, S Ghatak - Pharmaceutics, 2024 - mdpi.com
Of all the numerous nanosized extracellular vesicles released by a cell, the endosomal-
originated exosomes are increasingly recognized as potential therapeutics, owing to their …

The road after cancer: biomaterials and tissue engineering approaches to mediate the tumor microenvironment post-cancer treatment

L Westwood, IJ Nixon, E Emmerson… - Frontiers in Biomaterials …, 2024 - frontiersin.org
Cancer affects tens of millions of the world's population each year with a stark mortality rate.
It is well established that in order to be effective in treating solid tumor cancers, the current …

Exosomes as new generation vehicles for drug delivery systems

N Dilsiz - Journal of Drug Delivery Science and Technology, 2024 - Elsevier
Exosomes are the smallest subtype of mobile extracellular vesicles (EVs), and round sacs
with a diameter between 30 and 120 nm are released by almost all cell types into the …

Exosome-mediated antigen delivery: unveiling novel strategies in viral infection control and vaccine design

D El Safadi, A Mokhtari, M Krejbich, A Lagrave… - Vaccines, 2024 - mdpi.com
Exosomes are small subtypes of extracellular vesicles (EVs) naturally released by different
types of cells into their environment. Their physiological roles appear to be multiple, yet …

Combinatory Nanovesicle with siRNA-Loaded Extracellular Vesicle and IGF-1 for Osteoarthritis Treatments

JY Kim, SY Lee, SG Cha, JM Park, DH Song… - International Journal of …, 2024 - mdpi.com
Extracellular vesicles (EVs) have been found to have the characteristics of their parent cells.
Based on the characteristics of these EVs, various studies on disease treatment using …