Liver ischaemia–reperfusion injury: a new understanding of the role of innate immunity

H Hirao, K Nakamura… - … reviews Gastroenterology & …, 2022 - nature.com
Liver ischaemia–reperfusion injury (LIRI), a local sterile inflammatory response driven by
innate immunity, is one of the primary causes of early organ dysfunction and failure after …

The neutrophil's role during health and disease

PX Liew, P Kubes - Physiological reviews, 2019 - journals.physiology.org
Neutrophils have always been considered as uncomplicated front-line troopers of the innate
immune system equipped with limited proinflammatory duties. Yet recently, the role of the …

Effects of immune cells and cytokines on inflammation and immunosuppression in the tumor microenvironment

L Li, R Yu, T Cai, Z Chen, M Lan, T Zou, B Wang… - International …, 2020 - Elsevier
Chronic inflammation and immune responses are two core element that characterize the
tumor microenvironment. A large number of immune/inflammatory cells (including tumor …

The regulatory roles of neutrophils in adaptive immunity

Y Li, W Wang, F Yang, Y Xu, C Feng, Y Zhao - Cell Communication and …, 2019 - Springer
Neutrophils have long been considered as cells playing a crucial role in the immune
defence against invading pathogens. Accumulating evidence strongly supported the direct …

The multifaceted functions of neutrophils

TN Mayadas, X Cullere… - Annual Review of …, 2014 - annualreviews.org
Neutrophils and neutrophil-like cells are the major pathogen-fighting immune cells in
organisms ranging from slime molds to mammals. Central to their function is their ability to …

FcγR engagement reprograms neutrophils into antigen cross-presenting cells that elicit acquired anti-tumor immunity

V Mysore, X Cullere, J Mears, F Rosetti… - Nature …, 2021 - nature.com
Classical dendritic cells (cDC) are professional antigen-presenting cells (APC) that regulate
immunity and tolerance. Neutrophil-derived cells with properties of DCs (nAPC) are …

Neutrophils acquire the capacity for antigen presentation to memory CD4+ T cells in vitro and ex vivo

M Vono, A Lin, A Norrby-Teglund… - Blood, The Journal …, 2017 - ashpublications.org
Neutrophils are critical cells of the innate immune system and rapidly respond to tissue
injury and infection. Increasing evidence also indicates that neutrophils have versatile …

[HTML][HTML] The role of neutrophils during intestinal inflammation

BM Fournier, CA Parkos - Mucosal immunology, 2012 - Elsevier
Polymorphonuclear leukocytes or neutrophils play a critical role in the maintenance of
intestinal homeostasis. They have elegant defense mechanisms to eliminate microbes that …

Immune suppression by neutrophils and granulocytic myeloid-derived suppressor cells: similarities and differences

J Pillay, T Tak, VM Kamp, L Koenderman - Cellular and molecular life …, 2013 - Springer
Neutrophils are essential effector cells in the host defense against invading pathogens.
Recently, novel neutrophil functions have emerged in addition to their classical anti …

New developments in neutrophil biology and periodontitis

G Hajishengallis - Periodontology 2000, 2020 - Wiley Online Library
Neutrophils have been historically associated with antimicrobial functions in acute infections
but are now appreciated as functionally versatile cells with critical roles in chronic …