Expression and function of idiotypes on lymphocytes

K Eichmann - Advances in immunology, 1978 - Elsevier
Publisher Summary This chapter summarizes a series of new procedures for the production
of anti-idiotypic reagents. It discusses the serological analysis of antigen receptors on …

Graft-versus-Host-Reactions: A Review

SC Grebe, JW Streilein - Advances in immunology, 1976 - Elsevier
Publisher Summary Graft-versus-host reactions (GVHRs) are one of the most intriguing
facets of transplantation immunology. This chapter describes the GVHRs, and mechanisms …

Self and non-sense: an organism-centered approach to immunology

NM Vaz, FJ Varela - Medical hypotheses, 1978 - Elsevier
This paper provides a conceptual framework to accommodate important recent
developments in immunology (genetic determination, cellular interactions, suppression) …

Idiotypic regulation of the immune system by the induction of antibodies against anti-idiotypic antibodies.

J Urbain, M Wikler, JD Franssen… - Proceedings of the …, 1977 - National Acad Sciences
Anticarbohydrate antibodies (Ab1) were isolated from a rabbit hyperimmunized with
Micrococcus lysodeikticus and injected into allotype-matched rabbits in order to obtain …

Detection of anti‐idiotype reactive cells in the response to phosphorylcholine

H Cosenza - European journal of immunology, 1976 - Wiley Online Library
Upon immunization with phosphorylcholine (PC), BALB/c mice produce antibodies bearing
mainly one idiotype which is identical to that of the TEPC 15 PC‐binding myeloma protein …

Autoantibodies to insulin receptor spontaneously develop as anti-idiotypes in mice immunized with insulin

Y Shechter, R Maron, D Elias, IR Cohen - Science, 1982 - science.org
Mice immunized with insulin developed antibodies to both insulin and the insulin receptor.
The antibodies to insulin receptor displaced labeled insulin from insulin receptors and …

Idiotype-anti-idiotype regulation. I. Immunization with a levan-binding myeloma protein leads to the appearance of auto-anti-(anti-idiotype) antibodies and to the …

CA Bona, E Heber-Katz, WE Paul - The Journal of experimental …, 1981 - rupress.org
BALB/c mice immunized multiple times with ABPC48 (A48 or Ab1), a BALB/c bacterial levan
(BL)-binding myeloma proteins, produce anti-Ab1 antibodies (Ab2). Immunization with only …

Recognition of immunoglobulin idiotypes by thymus-derived lymphocytes.

CA Janeway Jr, N Sakato… - Proceedings of the …, 1975 - National Acad Sciences
The ability of thymus-derived lymphocytes (T cells) from BALB/c mice to recognize the
individually specific antigenic determinants (idiotypes) of BALB/c myeloma proteins was …

Antibodies to idiotypes of isologous immunoglobulins.

N Sakato, HN Eisen - The Journal of experimental medicine, 1975 - rupress.org
To determine if the immunoglobulins (Igs) capable of eliciting the formation of isologous anti-
idiotypic antibodies are rare exceptions, BABL/c mice were immunized with five myeloma …

Neutralizing antiidiotypic antibodies to factor VIII inhibitors after desensitization in patients with hemophilia A.

JG Gilles, B Desqueper, H Lenk… - The Journal of …, 1996 - Am Soc Clin Investig
Hemophilia A patients producing antibodies towards FVIII are usually treated with infusions
of high doses of FVIII in an attempt to" desensitize" them. To examine the mechanisms by …