Background Angiotensin converting enzyme inhibitors (ACE‐I) and angiotensin receptor
blockers (ARB) exhibit beneficial antidiabetic effects in patients with type 2 diabetes …

Objective To investigate whether gallstone disease (GD) increases the risk of developing
cardiovascular disease (CVD) in a large population-based cohort. Methods A study …

This year, 2022, marks the 100th anniversary of the isolation of human insulin and its
administration to patients suffering from diabetes mellitus (DM). Insulin exerts many effects …

Circulating insulin-like growth factor-1 (IGF-1) levels are linked to cardiac performance and
lifespan. However, the role of IGF-1 levels in aging-associated cardiac dysfunction has not …

IGF-I has been suggested to be of importance for cardiovascular structure and function, but
the relative role of locally produced and liver-derived endocrine IGF-I remains unclear …

Insulin-like growth factor (IGF)-induced signaling networks are vital in modulating multiple
fundamental cellular processes, such as cell growth, survival, proliferation, and …

IGF-I rescues diabetic heart defects and oxidative stress, although the underlying
mechanism of action remains poorly understood. This study was designed to delineate the …

A fall in circulating levels of cardiac survival factor insulin‐like growth factor 1 (IGF‐1)
contributes to cardiac aging. To better understand the role of IGF‐1 in cardiac aging, we …

Prolactin receptor (PRL-R) expression in the brain is increased in lactating rats compared
with non-pregnant animals. The aim of the present study was to determine the time-course of …

The focus of the present review is on how interference with various ion channels in the heart
may be the molecular basis for cardiac side‐effects of gaseous anesthetics …