Parkinson's disease (PD) is a neurodegenerative disorder characterized by the progressive
degeneration of monoaminergic central pathways such as the serotonergic. The …

Neuro-inflammation in Parkinson's disease (PD) is associated with glial cell activation and
production of different inflammatory cytokines. In this study we investigated the effect of …

Abstract Serotonin‐6 (5‐HT6) receptors are densely expressed in the dorsolateral striatum
(DLS), a brain region linked to habits. Medications acting on the serotonergic system …

Serotonergic innervation of the CNS originates from the raphe nuclei and exerts widespread
influence on behavior. Serotonin (5-hydroxytryptamine, 5-HT) has an important …

In rodents, cortical information is transferred to the substantia nigra pars reticulata (SNr)
through motor and medial prefrontal (mPF) basal ganglia (BG) circuits implicated in motor …

5-HT plays a regulatory role in voluntary movements of the basal ganglia and has a major
impact on disorders of the basal ganglia such as Parkinson's disease (PD). Clinical studies …

6‐Hydroxydopamine (6‐OHDA) is a neurotoxic compound commonly used to induce
dopamine (DA) depletion in the nigrostriatal system, mimicking Parkinson's disease (PD) in …

This review explores the role of the antisaccadic task in understanding inhibitory
mechanisms in basal ganglia disorders. It conducts a comparative analysis of saccadic …

Medium spiny neurons (MSNs) constitute 95% of neurons in the dorsal striatum subdivided
into direct (striatonigral) and indirect (striatopallidal) pathways. Whereas D 1 and D 2 …

Objective Although attention-deficit/hyperactivity disorder (ADHD) is 1 of the most common
neurodevelopmental disorders, little is known about the neurobiology. Clinical studies …