Microenvironment-driven intratumoral heterogeneity in head and neck cancers: clinical challenges and opportunities for precision medicine

H Zaryouh, M Vara-Messler, J Vignau… - Drug Resistance …, 2022 - Elsevier
Squamous cell carcinoma of the head and neck (SCCHN) is among the most prevalent
cancer types worldwide. Despite multimodal therapeutic approaches that include surgical …

Boron neutron capture therapy: Current status and challenges

S Wang, Z Zhang, L Miao, Y Li - Frontiers in Oncology, 2022 - frontiersin.org
Boron neutron capture therapy (BNCT) is a re-emerging therapy with the ability to selectively
kill tumor cells. After the boron delivery agents enter the tumor tissue and enrich the tumor …

Epidemiological trends of head and neck cancer: a population‐based study

K Guo, W Xiao, X Chen, Z Zhao, Y Lin… - BioMed research …, 2021 - Wiley Online Library
Background. Over the past decades, lots of advance have occurred in the prevention,
diagnosis, and treatment of head and neck cancer (HNC). However, the contemporaneous …

Characterization of interplay between autophagy and ferroptosis and their synergistical roles on manipulating immunological tumor microenvironment in squamous …

L Chen, X Niu, X Qiao, S Liu, H Ma, X Shi… - Frontiers in …, 2022 - frontiersin.org
Objective Squamous cell carcinomas (SCCs) with shared etiology, histological
characteristics, and certain risk factors represent the most common solid cancers. This study …

Targeting metabolism to overcome cancer drug resistance: A promising therapeutic strategy for diffuse large B cell lymphoma

M Pi, H Kuang, C Yue, Q Yang, A Wu, Y Li… - Drug Resistance …, 2022 - Elsevier
Cancer cell metabolism including aerobic glycolysis, amino acid and fatty acid metabolism,
has been extensively studied. Metabolic reprogramming is a major hallmark of cancer …

Identification and validation of neurotrophic factor-related genes signature in HNSCC to predict survival and immune landscapes

G Peng, H Chi, X Gao, J Zhang, G Song, X Xie… - Frontiers in …, 2022 - frontiersin.org
Background: Head and neck squamous cell carcinoma (HNSCC) is the seventh most
common type of cancer worldwide. Its highly aggressive and heterogeneous nature and …

[HTML][HTML] New insights into the pharmacological, immunological, and CAR-T-cell approaches in the treatment of hepatocellular carcinoma

M Dal Bo, E De Mattia, L Baboci, S Mezzalira… - Drug Resistance …, 2020 - Elsevier
The tyrosine kinase inhibitor (TKI) sorafenib continues to be the anchor drug in the treatment
of advanced stage hepatocellular carcinoma (HCC). Other TKIs as well as immune …

[HTML][HTML] Human papillomavirus-associated head and neck cancers. Where are we now? A systematic review

M Pinkiewicz, K Dorobisz, T Zatoński - Cancer Management and …, 2022 - ncbi.nlm.nih.gov
Background Human papillomavirus targets the skin and mucous membranes, producing
benign hyperplastic lesions and precancerous and cancerous lesions. An increasing …

Nasopharyngeal carcinoma: A new synthesis of literature data

D Jicman, E Niculet, M Lungu… - Experimental and …, 2022 - spandidos-publications.com
Nasopharyngeal carcinoma (NPC) is an epithelial tumor, which develops most frequently
from the lateral pharyngeal recess and holds some complex epidemiological characteristics …

Why may citrate sodium significantly increase the effectiveness of transarterial chemoembolization in hepatocellular carcinoma?

P Icard, L Simula, Z Wu, D Berzan, P Sogni… - Drug Resistance …, 2021 - Elsevier
Hepatocellular carcinoma (HCC) represents the third cause of cancer death in men
worldwide, and its increasing incidence can be explained by the increasing occurrence of …