Exercise training and DNA methylation in humans
The response to exercise training (trainability) has been shown to have a strong heritable
component. There is growing evidence suggesting that traits such as trainability do not only …
component. There is growing evidence suggesting that traits such as trainability do not only …
Advances in exercise, fitness, and performance genomics in 2015.
A small number of excellent papers on exercise genomics issues have been published in
2012. A new PYGM knock-in mouse model will provide opportunities to investigate the …
2012. A new PYGM knock-in mouse model will provide opportunities to investigate the …
[HTML][HTML] The ACTN3 R577X Polymorphism across Three Groups of Elite Male European Athletes
The ACTN3 R577X polymorphism (rs1815739) is a strong candidate to influence elite
athletic performance. Yet, controversy exists in the literature owing to between-studies …
athletic performance. Yet, controversy exists in the literature owing to between-studies …
Genomics of elite sporting performance: what little we know and necessary advances
Numerous reports of genetic associations with performance-and injury-related phenotypes
have been published over the past three decades; these studies have employed primarily …
have been published over the past three decades; these studies have employed primarily …
ACTN3 R577X genotype is associated with sprinting in elite Japanese athletes
E Mikami, N Fuku, H Murakami… - … journal of sports …, 2014 - thieme-connect.com
The ACTN3 R577X genotype has been found to associate with sprint/power phenotypes in
all elite athlete cohorts investigated. This association has not been extensively studied in …
all elite athlete cohorts investigated. This association has not been extensively studied in …
[HTML][HTML] Advances in exercise, fitness, and performance genomics in 2012
L Pérusse, T Rankinen, JM Hagberg… - Medicine and science …, 2013 - ncbi.nlm.nih.gov
A small number of excellent papers on exercise genomics issues have been published in
2012. A new PYGM knock-in mouse model will provide opportunities to investigate the …
2012. A new PYGM knock-in mouse model will provide opportunities to investigate the …
ACTN3 genotype and modulation of skeletal muscle response to exercise in human subjects
B Norman, M Esbjörnsson… - Journal of applied …, 2014 - journals.physiology.org
α-Actinin-3 is a Z-disc protein expressed only in type II muscle fibers. A polymorphism in the
ACTN3 gene (R577X) results in lack of α-actinin-3 in XX genotype. The prevalence of the …
ACTN3 gene (R577X) results in lack of α-actinin-3 in XX genotype. The prevalence of the …
[HTML][HTML] Role of alpha-actinin-3 in contractile properties of human single muscle fibers: a case series study in paraplegics
A common nonsense polymorphism in the ACTN3 gene results in the absence of α-actinin-3
in XX individuals. The wild type allele has been associated with power athlete status and an …
in XX individuals. The wild type allele has been associated with power athlete status and an …
Mechanisms governing the health and performance benefits of exercise
D Bishop‐Bailey - British journal of pharmacology, 2013 - Wiley Online Library
Humans are considered among the greatest if not the greatest endurance land animals.
Over the last 50 years, as the population has become more sedentary, rates of …
Over the last 50 years, as the population has become more sedentary, rates of …
α-Actinin-3 deficiency alters muscle adaptation in response to denervation and immobilization
Homozygosity for a common null polymorphism (R577X) in the ACTN3 gene results in the
absence of the fast fibre-specific protein, α-actinin-3 in∼ 16% of humans worldwide. α …
absence of the fast fibre-specific protein, α-actinin-3 in∼ 16% of humans worldwide. α …