Epigenomics of leukemia: from mechanisms to therapeutic applications

C Florean, M Schnekenburger, C Grandjenette… - …, 2011 - Taylor & Francis
Leukemogenesis is a multistep process in which successive transformational events
enhance the ability of a clonal population arising from hematopoietic progenitor cells to …

KAT (ching) metabolism by the tail: insight into the links between lysine acetyltransferases and metabolism

BN Albaugh, KM Arnold, JM Denu - Chembiochem, 2011 - Wiley Online Library
Post‐translational modifications of histones elicit structural and functional changes within
chromatin that regulate various epigenetic processes. Epigenetic mechanisms rely on …

Studying the lysine acetylation of malate dehydrogenase

S Venkat, C Gregory, J Sturges, Q Gan… - Journal of molecular …, 2017 - Elsevier
Protein acetylation plays important roles in many biological processes. Malate
dehydrogenase (MDH), a key enzyme in the tricarboxylic acid cycle, has been identified to …

Differential lysine acetylation profiles of Erwinia amylovora strains revealed by proteomics

X Wu, A Vellaichamy, D Wang, L Zamdborg… - Journal of …, 2013 - Elsevier
Protein lysine acetylation (LysAc) has recently been demonstrated to be widespread in E.
coli and Salmonella, and to broadly regulate bacterial physiology and metabolism. However …

Stress responsive mitochondrial proteins in Arabidopsis thaliana

Y Wang, O Berkowitz, J Selinski, Y Xu… - Free Radical Biology …, 2018 - Elsevier
In the last decade plant mitochondria have emerged as a target, sensor and initiator of
signalling cascades to a variety of stress and adverse growth conditions. A combination of …

Protein targets of thioacetamide metabolites in rat hepatocytes

YM Koen, D Sarma, H Hajovsky… - Chemical research in …, 2013 - ACS Publications
Thioacetamide (TA) has long been known as a hepatotoxicant whose bioactivation requires
S-oxidation to thioacetamide S-oxide (TASO) and then to the very reactive S, S-dioxide …

A histone deacetylase, Magnaporthe oryzae RPD3, regulates reproduction and pathogenic development in the rice blast fungus

SH Lee, MEA Farh, J Lee, YT Oh, E Cho, J Park, H Son… - MBio, 2021 - Am Soc Microbiol
Acetylation and deacetylation of histones are key epigenetic mechanisms for gene
regulation in response to environmental stimuli. RPD3 is a well-conserved class I histone …

[HTML][HTML] VDAC proteomics: post-translation modifications

J Kerner, K Lee, B Tandler, CL Hoppel - Biochimica et Biophysica Acta …, 2012 - Elsevier
Voltage-dependent anion channels are abundant mitochondrial outer membrane proteins
expressed in three isoforms, VDAC1-3, and are considered as “mitochondrial gatekeepers” …

Acetyl-CoA from inflammation-induced fatty acids oxidation promotes hepatic malate-aspartate shuttle activity and glycolysis

T Wang, W Yao, J Li, Q He, Y Shao… - American Journal of …, 2018 - journals.physiology.org
Hepatic metabolic syndrome is associated with inflammation, as inflammation stimulates the
reprogramming of nutrient metabolism and hepatic mitochondria-generated acetyl-CoA, but …

The Mechanism of Variegation in immutans Provides Insight into Chloroplast Biogenesis

A Foudree, A Putarjunan, S Kambakam… - Frontiers in Plant …, 2012 - frontiersin.org
The immutans (im) variegation mutant of Arabidopsis has green and white-sectored leaves
due to the absence of fully functional plastid terminal oxidase (PTOX), a plastoquinol …