Epigenomics of leukemia: from mechanisms to therapeutic applications
C Florean, M Schnekenburger, C Grandjenette… - …, 2011 - Taylor & Francis
Leukemogenesis is a multistep process in which successive transformational events
enhance the ability of a clonal population arising from hematopoietic progenitor cells to …
enhance the ability of a clonal population arising from hematopoietic progenitor cells to …
KAT (ching) metabolism by the tail: insight into the links between lysine acetyltransferases and metabolism
BN Albaugh, KM Arnold, JM Denu - Chembiochem, 2011 - Wiley Online Library
Post‐translational modifications of histones elicit structural and functional changes within
chromatin that regulate various epigenetic processes. Epigenetic mechanisms rely on …
chromatin that regulate various epigenetic processes. Epigenetic mechanisms rely on …
Studying the lysine acetylation of malate dehydrogenase
S Venkat, C Gregory, J Sturges, Q Gan… - Journal of molecular …, 2017 - Elsevier
Protein acetylation plays important roles in many biological processes. Malate
dehydrogenase (MDH), a key enzyme in the tricarboxylic acid cycle, has been identified to …
dehydrogenase (MDH), a key enzyme in the tricarboxylic acid cycle, has been identified to …
Differential lysine acetylation profiles of Erwinia amylovora strains revealed by proteomics
Protein lysine acetylation (LysAc) has recently been demonstrated to be widespread in E.
coli and Salmonella, and to broadly regulate bacterial physiology and metabolism. However …
coli and Salmonella, and to broadly regulate bacterial physiology and metabolism. However …
Stress responsive mitochondrial proteins in Arabidopsis thaliana
In the last decade plant mitochondria have emerged as a target, sensor and initiator of
signalling cascades to a variety of stress and adverse growth conditions. A combination of …
signalling cascades to a variety of stress and adverse growth conditions. A combination of …
Protein targets of thioacetamide metabolites in rat hepatocytes
YM Koen, D Sarma, H Hajovsky… - Chemical research in …, 2013 - ACS Publications
Thioacetamide (TA) has long been known as a hepatotoxicant whose bioactivation requires
S-oxidation to thioacetamide S-oxide (TASO) and then to the very reactive S, S-dioxide …
S-oxidation to thioacetamide S-oxide (TASO) and then to the very reactive S, S-dioxide …
A histone deacetylase, Magnaporthe oryzae RPD3, regulates reproduction and pathogenic development in the rice blast fungus
Acetylation and deacetylation of histones are key epigenetic mechanisms for gene
regulation in response to environmental stimuli. RPD3 is a well-conserved class I histone …
regulation in response to environmental stimuli. RPD3 is a well-conserved class I histone …
[HTML][HTML] VDAC proteomics: post-translation modifications
J Kerner, K Lee, B Tandler, CL Hoppel - Biochimica et Biophysica Acta …, 2012 - Elsevier
Voltage-dependent anion channels are abundant mitochondrial outer membrane proteins
expressed in three isoforms, VDAC1-3, and are considered as “mitochondrial gatekeepers” …
expressed in three isoforms, VDAC1-3, and are considered as “mitochondrial gatekeepers” …
Acetyl-CoA from inflammation-induced fatty acids oxidation promotes hepatic malate-aspartate shuttle activity and glycolysis
T Wang, W Yao, J Li, Q He, Y Shao… - American Journal of …, 2018 - journals.physiology.org
Hepatic metabolic syndrome is associated with inflammation, as inflammation stimulates the
reprogramming of nutrient metabolism and hepatic mitochondria-generated acetyl-CoA, but …
reprogramming of nutrient metabolism and hepatic mitochondria-generated acetyl-CoA, but …
The Mechanism of Variegation in immutans Provides Insight into Chloroplast Biogenesis
A Foudree, A Putarjunan, S Kambakam… - Frontiers in Plant …, 2012 - frontiersin.org
The immutans (im) variegation mutant of Arabidopsis has green and white-sectored leaves
due to the absence of fully functional plastid terminal oxidase (PTOX), a plastoquinol …
due to the absence of fully functional plastid terminal oxidase (PTOX), a plastoquinol …