Coordination of microtubule acetylation and the actin cytoskeleton by formins

J Fernández-Barrera, MA Alonso - Cellular and molecular life sciences, 2018 - Springer
The acetylation of the lysine 40 residue of α-tubulin was described more than 30 years ago
and has been the subject of intense research ever since. Although the exact function of this …

Revealing dynamic protein acetylation across subcellular compartments

J Baeza, AJ Lawton, J Fan, MJ Smallegan… - Journal of proteome …, 2020 - ACS Publications
Protein acetylation is a widespread post-translational modification implicated in many
cellular processes. Recent advances in mass spectrometry have enabled the cataloging of …

Lysine acetylation stoichiometry and proteomics analyses reveal pathways regulated by sirtuin 1 in human cells

J Gil, A Ramírez-Torres, D Chiappe… - Journal of Biological …, 2017 - ASBMB
Lysine acetylation is a widespread posttranslational modification affecting many biological
pathways. Recent studies indicate that acetylated lysine residues mainly exhibit low …

Histone deacetylase inhibitors modulate miRNA and mRNA expression, block metaphase, and induce apoptosis in inflammatory breast cancer cells

N Chatterjee, WLW Wang, T Conklin… - Cancer biology & …, 2013 - Taylor & Francis
To develop new therapies for inflammatory breast cancer (IBC) we have compared the
effects of two hydroxamic acid-based histone deacetylase (HDAC) inhibitors, CG-1521 and …

A molecularly imprinted polymer as an antibody mimic with affinity for lysine acetylated peptides

X Yang, X Dong, K Zhang, F Yang… - Journal of Materials …, 2016 - pubs.rsc.org
Lysine acetylation is a widespread protein post-translational modification (PTM) that plays a
central role in diverse physiological processes. The study on the scope and pattern of lysine …

Insights into the lysine acetylproteome of human sperm

G Sun, M Jiang, T Zhou, Y Guo, Y Cui, X Guo, J Sha - Journal of proteomics, 2014 - Elsevier
Protein lysine acetylation is a dynamic and reversible post-modification that is known to play
diverse functions in eukaryotes. Nevertheless, the composition and function of non-histone …

Acetylation of the RhoA GEF Net1A controls its subcellular localization and activity

EH Song, W Oh, A Ulu, HS Carr, Y Zuo… - Journal of cell …, 2015 - journals.biologists.com
ABSTRACT Net1 isoform A (Net1A) is a RhoA GEF that is required for cell motility and
invasion in multiple cancers. Nuclear localization of Net1A negatively regulates its activity …

Small molecule modulators of histone acetylation and methylation: a disease perspective

BR Selvi, DV Mohankrishna, YB Ostwal… - Biochimica et Biophysica …, 2010 - Elsevier
Chromatin modifications have gained immense significance in the past few decades as key
regulators of gene expression. The enzymes responsible for these modifications along with …

Genetically encoding thioacetyl‐lysine as a non‐deacetylatable analog of lysine acetylation in Escherichia coli

S Venkat, DT Nannapaneni, C Gregory, Q Gan… - FEBS Open …, 2017 - Wiley Online Library
Reversible lysine acetylation is one of the most widely distributed post‐translational
modifications; it is involved in a variety of biological processes and can be found in all three …

Plant mitochondrial retrograde signaling: post-translational modifications enter the stage

M Hartl, I Finkemeier - Frontiers in plant science, 2012 - frontiersin.org
Beside their central function in respiration plant mitochondria play important roles in diverse
processes such as redox homeostasis, provision of precursor molecules for essential …