Effects of monoterpenes on ion channels of excitable cells

M Oz, Y Lozon, A Sultan, KHS Yang… - Pharmacology & …, 2015 - Elsevier
Monoterpenes are a structurally diverse group of phytochemicals and a major constituent of
plant-derived 'essential oils'. Monoterpenes such as menthol, carvacrol, and eugenol have …

A highly contiguous genome assembly reveals sources of genomic novelty in the symbiotic fungus Rhizophagus irregularis

BF Manley, JS Lotharukpong… - G3: Genes …, 2023 - academic.oup.com
The root systems of most plant species are aided by the soil-foraging capacities of symbiotic
arbuscular mycorrhizal (AM) fungi of the Glomeromycotina subphylum. Despite recent …

Data-driven analysis of TRP channels in cancer: linking variation in gene expression to clinical significance

YR Park, JN Chun, I So, HJ Kim, S Baek… - Cancer genomics & …, 2016 - cgp.iiarjournals.org
Background: Experimental evidence has suggested that transient receptor potential (TRP)
channels play a crucial role in tumor biology. However, clinical relevance and significance of …

TRP channels in cardiac and intestinal fibrosis

R Inoue, LH Kurahara, K Hiraishi - Seminars in Cell & Developmental …, 2019 - Elsevier
It is now widely accepted that advanced fibrosis underlies many chronic inflammatory
disorders and is the main cause of morbidity and mortality of the modern world. The …

Actions and regulation of ionotropic cannabinoid receptors

L De Petrocellis, M Nabissi, G Santoni… - Advances in …, 2017 - Elsevier
Almost three decades have passed since the identification of the two specific metabotropic
receptors mediating cannabinoid pharmacology. Thereafter, many cannabinoid effects, both …

Effect of capsaicin on thermoregulation: an update with new aspects

J Szolcsányi - Temperature, 2015 - Taylor & Francis
Capsaicin, a selective activator of the chemo-and heat-sensitive transient receptor potential
(TRP) V1 cation channel, has characteristic feature of causing long-term functional and …

Mechanoregulatory role of TRPV4 in prenatal skeletal development

NS Khatib, J Monsen, S Ahmed, Y Huang, DA Hoey… - Science …, 2023 - science.org
Biophysical cues are essential for guiding skeletal development, but the mechanisms
underlying the mechanical regulation of cartilage and bone formation are unknown. TRPV4 …

Evidence for the role of lipid rafts and sphingomyelin in Ca2+-gating of Transient Receptor Potential channels in trigeminal sensory neurons and peripheral nerve …

É Sághy, É Szőke, M Payrits, Z Helyes, R Börzsei… - Pharmacological …, 2015 - Elsevier
Abstract Transient Receptor Potential (TRP) cation channels, such as TRP Vanilloid 1 and
TRP Ankyrin repeat domain 1 (TRPV1 and TRPA1) are nocisensors playing important role to …

Transient receptor potential canonical (TRPC)/Orai1-dependent store-operated Ca2+ channels: new targets of aldosterone in cardiomyocytes

J Sabourin, F Bartoli, F Antigny, AM Gomez… - Journal of Biological …, 2016 - ASBMB
Store-operated Ca 2+ entry (SOCE) has emerged as an important mechanism in cardiac
pathology. However, the signals that up-regulate SOCE in the heart remain unexplored …

New natural agonists of the transient receptor potential Ankyrin 1 (TRPA1) channel

C Legrand, JM Merlini, C de Senarclens-Bezençon… - Scientific reports, 2020 - nature.com
The transient receptor potential (TRP) channels family are cationic channels involved in
various physiological processes as pain, inflammation, metabolism, swallowing function, gut …