Design, Synthesis and Biological Evaluation of Glycosylated Derivatives of Silibinin as Potential Anti-Tumor Agents

JJ Xi, Y Cao, RY He, JK Zhang, YM Zhao… - Drug Design …, 2023 - Taylor & Francis
Objective Silibinin, a natural product extracted from the seeds of the Silybum marianum, is
versatile with various pharmacological effects. However, its clinical application was strongly …

Efficient synthesis and biological evaluation of some new series of pyridine derivatives: Promising and potent new class of anticancer agents

HAS Abbas, EA Abo Zeina, HA Radwan… - Journal of …, 2022 - Wiley Online Library
In an attempt to develop potent anticancer agents, we have synthesized some substituted
pyridine derivatives. Alkylation of the pyridine‐3‐carbonitrile 1a by chloroacetonitrile or …