Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …

Diverse ecologically important metabolites, such as allelochemicals, infochemicals and
volatile organic chemicals, are involved in marine organismal interactions. Chemically …

The human microbiome and its metabolic output play an important role in shaping human
health and disease. The host-microbe crosstalk is often characterised using metabolomics …

Covering: 1995 to 2023Advances in bioanalytical methods, particularly mass spectrometry,
have provided valuable molecular insights into the mechanisms of life. Non-targeted …

Covering: marine indole alkaloids (n= 2048) and their reported bioactivities up to the end of
2021 Despite increasing numbers of marine natural products (MNPs) reported each year …

Among the plant‐associated microorganisms, the so‐called endophytes continue to attract
much attention because of their ability not only to protect host plants from biotic and abiotic …

Co-cultivation is an effective method of inducing the production of specialized metabolites
(SMs) in microbial strains. By mimicking the ecological interactions that take place in natural …

Covering: September 1964 to June 2023Bacteria and fungi living in symbiosis with insects
have been studied over the last sixty years and found to be important sources of bioactive …

Culture-independent and culture-dependent approaches were employed to investigate the
taxonomic diversity and biosynthetic gene cluster potential of Actinomycetota in the Mekong …

Polycyclic tetramate macrolactams (PTMs) are bioactive natural products commonly
associated with certain actinobacterial and proteobacterial lineages. These molecules have …