[HTML][HTML] Vascular dysfunction in preeclampsia

MA Opichka, MW Rappelt, DD Gutterman, JL Grobe… - Cells, 2021 - mdpi.com
Preeclampsia is a life-threatening pregnancy-associated cardiovascular disorder
characterized by hypertension and proteinuria at 20 weeks of gestation. Though its exact …

[HTML][HTML] Role of oxidative stress in the dysfunction of the placental endothelial nitric oxide synthase in preeclampsia

P Guerby, O Tasta, A Swiader, F Pont, E Bujold… - Redox biology, 2021 - Elsevier
Preeclampsia (PE) is a multifactorial pregnancy disease, characterized by new-onset
gestational hypertension with (or without) proteinuria or end-organ failure, exclusively …

[HTML][HTML] Oxidative stress: Normal pregnancy versus preeclampsia

DI Chiarello, C Abad, D Rojas, F Toledo… - … et Biophysica Acta (BBA …, 2020 - Elsevier
The role of oxidative stress in the physiopathology of human pregnancy is of particular
interest. Pregnancy is well-known to increase the oxidative stress, mainly produced by a …

[HTML][HTML] The pivotal role of the placenta in normal and pathological pregnancies: a focus on preeclampsia, fetal growth restriction, and maternal chronic venous …

MA Ortega, O Fraile-Martínez, C García-Montero… - Cells, 2022 - mdpi.com
The placenta is a central structure in pregnancy and has pleiotropic functions. This organ
grows incredibly rapidly during this period, acting as a mastermind behind different fetal and …

Evidence for the presence of air pollution nanoparticles in placental tissue cells

NM Liu, L Miyashita, BA Maher, G McPhail… - Science of The Total …, 2021 - Elsevier
Inhaled particulate matter (PM) from combustion-and friction-sourced air pollution adversely
affects organs distant from the lung. A putative mechanism for the remote effect of inhaled …

Placental trophoblast cell differentiation: physiological regulation and pathological relevance to preeclampsia

L Ji, J Brkić, M Liu, G Fu, C Peng, YL Wang - Molecular aspects of medicine, 2013 - Elsevier
The placenta is a transient organ that forms during pregnancy to support the growth and
development of the fetus. During human placental development, trophoblast cells …

The Impact of IgG transplacental transfer on early life immunity

GG Fouda, DR Martinez, GK Swamy, SR Permar - Immunohorizons, 2018 - journals.aai.org
Pediatric vaccines have significantly reduced infectious disease–related infant mortality, but
as protective immunity often requires several infant vaccine doses, maternally acquired Abs …

Reconciling the distinct roles of angiogenic/anti-angiogenic factors in the placenta and maternal circulation of normal and pathological pregnancies

A Umapathy, LW Chamley, JL James - Angiogenesis, 2020 - Springer
A branched vascular network is crucial to placental development and is dependent on
factors such as vascular endothelial growth factor (VEGF), placental growth factor (PlGF) …

Gestational hypoxia and developmental plasticity

CA Ducsay, R Goyal, WJ Pearce… - Physiological …, 2018 - journals.physiology.org
Hypoxia is one of the most common and severe challenges to the maintenance of
homeostasis. Oxygen sensing is a property of all tissues, and the response to hypoxia is …

Angiogenesis in the placenta: the role of reactive oxygen species signaling

RD Pereira, NE De Long, RC Wang… - BioMed research …, 2015 - Wiley Online Library
Proper placental development and function are central to the health of both the mother and
the fetus during pregnancy. A critical component of healthy placental function is the proper …