Honokiol reduces fungal burden and ameliorate inflammation lesions of Aspergillus fumigatus keratitis via Dectin-2 down-regulation

L Zhan, X Tian, J Lin, Y Zhang, H Zheng, X Peng… - International …, 2023 - Elsevier
Purpose To screen and identify the mechanism of honokiol on anti-fungi and anti-
inflammation in fungal keratitis (FK) through bioinformatic analysis and biological …

[HTML][HTML] General morphological characteristics of the results of experimental modeling of aseptic peritonitis

V Hryn, Y Kostylenko, O Maksymenko - Annals of Anatomy-Anatomischer …, 2023 - Elsevier
Background Aseptic peritonitis is a reaction of the local immune system aimed at rejection of
a foreign body, which, having antigenic properties, does not (unlike a pathogen) counteract …

Peripheral inflammation-induced changes in songbird brain gene expression: 3'mRNA transcriptomic approach

NK Veetil, HC de Oliveira, M Gomez-Samblas… - Developmental & …, 2024 - Elsevier
Species-specific neural inflammation can be induced by profound immune signalling from
periphery to brain. Recent advances in transcriptomics offer cost-effective approaches to …

TAK‐242 Ameliorates Hepatic Fibrosis by Regulating the Liver‐Gut Axis

S Liu, J Wu, P Chen, SAD Mohammed… - BioMed Research …, 2022 - Wiley Online Library
Objective. The aims of this study were to investigate the impact of TAK‐242 on the Toll‐like
receptor 4 (TLR4)/myeloid differentiation factor 88 (MyD88)/nuclear transcription factor‐κB …

[HTML][HTML] 3D-QSAR and Molecular Dynamics Study of Isoxazole Derivatives to Identify the Structural Requirements for Farnesoid X Receptor (FXR) Agonists

D Yan, Y Yang, H Shen, Z Liu, K Yao, Q Liu - Molecules, 2024 - mdpi.com
The farnesoid X receptor (FXR) has been recognized as a potential drug target for the
treatment of non-alcoholic fatty liver disease (NAFLD). FXR agonists benefit NAFLD by …