Recent advances in the treatment of Alzheimer's disease using nanoparticle-based drug delivery systems

P Poudel, S Park - Pharmaceutics, 2022 - mdpi.com
Alzheimer's disease (AD) is an irreversible and progressive neurodegenerative disorder.
Most existing treatments only provide symptomatic solutions. Here, we introduce currently …

[HTML][HTML] Beyond Tissue replacement: The Emerging role of smart implants in healthcare

E Abyzova, E Dogadina, RD Rodriguez, I Petrov… - Materials Today Bio, 2023 - Elsevier
Smart implants are increasingly used to treat various diseases, track patient status, and
restore tissue and organ function. These devices support internal organs, actively stimulate …

Biochemical profiling of berberine-enriched extract in aluminum chloride induced oxidative damage and neuroinflammation

MSH Akash, M Akbar, K Rehman, MA Shah… - … Science and Pollution …, 2023 - Springer
Despite the numerous treatment strategies used for Alzheimer's disease (AD), only a few
cholinesterase inhibitor drugs, such as memantine, are effective in symptomatically relieving …

Zinc ortho methyl carbonodithioate improved pre and post-synapse memory impairment via sirt1/P-jnk pathway against scopolamine in adult mice

R Jahan, M Yousaf, H Khan, SA Shah, AA Khan… - Journal of Neuroimmune …, 2023 - Springer
Alzheimer's disease (AD) is globally recognized as a prominent cause of dementia for which
efficient treatment is still lacking. New candidate compounds that are biologically potent are …

WIN55,212-2 Attenuates Cognitive Impairments in AlCl3 + d-Galactose-Induced Alzheimer's Disease Rats by Enhancing Neurogenesis and Reversing Oxidative …

O Mahdi, SM Chiroma, MT Hidayat Baharuldin… - Biomedicines, 2021 - mdpi.com
Neurotransmission and cognitive dysfunctions have been linked to old age disorders
including Alzheimer's disease (AD). Aluminium is a known neurotoxic metal, whereas d …

Vitamin D3 supplementation ameliorates cognitive impairment and alters neurodegenerative and inflammatory markers in scopolamine induced rat model

P Patel, J Shah - Metabolic Brain Disease, 2022 - Springer
A multifaceted approach can be effective for the treatment of dementia including the most
common form, Alzheimer's disease (AD). However, currently, it involves only symptomatic …

Novel Neuroprotective Potential of Bunchosia armeniaca (Cav.) DC against Lipopolysaccharide Induced Alzheimer's Disease in Mice

HA Abbas, AM Salama, SA El-Toumy, AA A. Salama… - Plants, 2022 - mdpi.com
Bunchosia armeniaca (Cav.) DC (Malpighiaceae) is one of the well-known traditionally used
remedies worldwide. This study aims to explore the leaves' metabolome via Quadrupole …

Advances in Alzheimer's disease therapeutics: biochemistry, exploring bioactive compounds and novel approaches

AV Atoki, PM Aja, EN Ondari… - International Journal of …, 2023 - Taylor & Francis
The most rampant and complex form of dementia is Alzheimer's disease (AD) which is
characterized by various cognitive deficits and personality abnormalities. AD is a …

Animal models of Alzheimer's disease: An origin of innovative treatments and insight to the disease's etiology

RS Chavan, KV Supalkar, SS Sadar, NS Vyawahare - Brain Research, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disorder. The main
pathogenic features are the development and deposition of senile plaques and …

A systematic review for the development of Alzheimer's disease in in vitro models: a focus on different inducing agents

M Prajapat, G Kaur, G Choudhary, P Pahwa… - Frontiers in Aging …, 2023 - frontiersin.org
Alzheimer's disease (AD) is the most common progressive neurodegenerative disease and
is associated with dementia. Presently, various chemical and environmental agents are …