Since the discovery of leucine-rich repeat kinase 2 (LRRK2) as a protein that is likely central
to the aetiology of Parkinson's disease, a considerable amount of work has gone into …

This review explores our current understanding of the complex interaction between
environmental risk factors, genetic traits and the development of inflammatory bowel …

Background The esophageal microbiome has been proposed to be involved in a range of
diseases including the esophageal adenocarcinoma cascade; however, little is currently …

Technological advances in the large scale analysis of human genetics have generated
profound insights into possible genetic contributions to chronic diseases including the …

Apple (Malus× domestica) is the third important fruit in terms of production and consumption
worldwide. Apple scab caused by Venturia inaequalis is the most devastating disease of …

Imaging genetics is a method used to detect associations between imaging and genetic
variables. Some researchers have used sparse canonical correlation analysis (SCCA) for …

Polymorphisms in leucine-rich repeat kinase 2 (LRRK2) have been linked to familial
Parkinson's disease, increased risk of sporadic Parkinson's disease, increased risk of …

Saliva functions in innate immunity of the oral cavity, protecting against demineralization of
teeth (ie dental caries), a highly prevalent infectious disease associated with Streptococcus …

The leucine-rich repeat kinase 2 mutation G2019S in the kinase-domain is the most
common genetic cause of Parkinson's disease. To investigate the impact of the G2019S …

Inflammatory bowel diseases (IBD), categorized as ulcerative colitis (UC), Crohn's disease
(CD), or IBD-undetermined (IBDU), are increasing in incidence. IBD is understood to result …