Confluence and convergence of Dscam and Pcdh cell-recognition codes
The ability of neurites of the same neuron to avoid each other (self-avoidance) is a
conserved feature in both invertebrates and vertebrates. The key to self-avoidance is the …
conserved feature in both invertebrates and vertebrates. The key to self-avoidance is the …
A universal residue numbering scheme for the Immunoglobulin-fold (Ig-fold) to study Ig-Proteomes and Ig-Interactomes
C Tawfeeq, J Wang, U Khaniya, T Madej, J Song… - bioRxiv, 2024 - biorxiv.org
ABSTRACT The Immunoglobulin fold (Ig-fold) is found in proteins from all domains of life
and represents the most populous fold in the human genome, with current estimates ranging …
and represents the most populous fold in the human genome, with current estimates ranging …
Clustered Protocadherin Cis-interactions are Required for Homophilic Combinatorial Cell-Cell Recognition Underlying Neuronal Self-Avoidance
G Wiseglass, N Boni, K Smorodinsky-Atias… - bioRxiv, 2023 - biorxiv.org
In the developing human brain, only 53 stochastically expressed clustered protocadherin
(cPcdh) isoforms enable neurites from an individual neuron to recognize and self-avoid …
(cPcdh) isoforms enable neurites from an individual neuron to recognize and self-avoid …