Liver disease and heart failure: Back and forth

M Correale, N Tarantino, R Petrucci, L Tricarico… - European journal of …, 2018 - Elsevier
In their clinical practice, physicians can face heart diseases (chronic or acute heart failure)
affecting the liver and liver diseases affecting the heart. Systemic diseases can also affect …

Mechanism-based inhibition of CYP450: an indicator of drug-induced hepatotoxicity

S Feng, X He - Current drug metabolism, 2013 - ingentaconnect.com
Xenobiotics are converted by cytochrome P450 (CYP450) into highly reactive metabolites
(RMs) that covalently bind to the catalytic site of the enzyme itself, subsequently causing …

Acute hepatotoxicity of intravenous amiodarone: case report and review of the literature

CC Chen, CC Wu - American journal of therapeutics, 2016 - journals.lww.com
Amiodarone is a class III antiarrhythmic drug widely used for the treatment of both
supraventricular and ventricular arrhythmias in intensive care unit. Hepatotoxicity of …

Hepatotoxicity of cardiovascular and antidiabetic drugs

D Halegoua-De Marzio, VJ Navarro - Drug-induced liver disease, 2013 - Elsevier
With the increasing prevalence of cardiovascular disease and associated disorders globally,
there has been a proliferation of medications for antiplatelet therapy, dyslipidemia, glycemic …

[HTML][HTML] Predictors of intravenous amiodarone induced liver injury

OA Diab, J Kamel, AA Abd-Elhamid - The Egyptian Heart Journal, 2017 - Elsevier
Background Intravenous (IV) amiodarone may be associated with liver injury that may
necessitate drug discontinuation. The prediction of amiodarone induced liver injury (AILI) …

A facile cell-involved microfluidic platform for assessing risk of hepatotoxic chemicals via on-line monitoring of multi-indexes

W Lu, B Huang, Y He, J Yang, Y Li - Sensors and Actuators B: Chemical, 2021 - Elsevier
Toxicity assessment is necessary in many fields, but the common animal experiments and
traditional cell-based bioassays are endpoint tests and limited in the aspects of cost …

[PDF][PDF] Severe acute hepatitis following intravenous amiodarone: a case report and review of the literature

A Stratton, J Fenderson, P Kenny, DL Helman - Acta gastro-enterologica …, 2015 - ageb.be
Abstract Background and Aims: Hepatotoxic complications of long-term oral amiodarone
therapy have been well described; however, liver injury secondary to parenteral infusion of …

[PDF][PDF] 胺碘酮引起的肝损伤

谢秋芬, 向倩, 周颖, 崔一民 - 药物不良反应杂志, 2014 - cadrj.com
I 类抗心律失常药胺碘酮可引起肝损伤, 发生率约为14%~ 82%. 胺碘酮致肝损伤的临床表现差异
较大. 包括无症状性肝酶水平升高, 暴发性肝衰竭甚至死亡. 组织病理学表现类似于酒精性肝病 …

胺碘酮致严重肝损害二例

范平, 周艳, 熊伟民 - 中华消化病与影像杂志: 电子版, 2013 - cqvip.com
胺碘酮为Ⅲ 类广谱抗心律失常药, 被广泛应用于临床治疗和预防各种室性,
室上性心律失常及心房颤动. 但在取得临床疗效的同时, 该药引起的肝脏损害亦较常见 …

[PDF][PDF] ФАКУЛТЕТ МЕДИЦИНСКИХ НАУКА УНИВЕРЗИТЕТ У КРАГУЈЕВЦУ

Ј Јовановић - medf.kg.ac.rs
Акутна хепатотоксичност је један од највећих проблема фармаковигиланце. Дијагноза
овог нежељеног дејства би требало да се заснива на клиничким критеријумима али и …