Pathogenesis and management of abdominal aortic aneurysm

J Golledge, S Thanigaimani, JT Powell… - European Heart …, 2023 - academic.oup.com
Abdominal aortic aneurysm (AAA) causes∼ 170 000 deaths annually worldwide. Most
guidelines recommend asymptomatic small AAAs (30 to< 50 mm in women; 30 to< 55 mm in …

Antithrombotic therapies in aortic and peripheral arterial diseases in 2021: a consensus document from the ESC working group on aorta and peripheral vascular …

V Aboyans, R Bauersachs, L Mazzolai… - European Heart …, 2021 - academic.oup.com
The aim of this collaborative document is to provide an update for clinicians on best
antithrombotic strategies in patients with aortic and/or peripheral arterial diseases …

[HTML][HTML] Editor's Choice–Association between metformin prescription and abdominal aortic aneurysm growth and clinical events: a systematic review and meta …

S Thanigaimani, TP Singh, J Unosson, J Phie… - European Journal of …, 2021 - Elsevier
Objective A meta-analysis of the association between metformin prescription and abdominal
aortic aneurysm (AAA) growth and events (rupture or surgical repair) was performed …

[HTML][HTML] Risk factors and mouse models of abdominal aortic aneurysm rupture

S Murali Krishna, SK Morton, J Li… - International Journal of …, 2020 - mdpi.com
Abdominal aortic aneurysm (AAA) rupture is an important cause of death in older adults. In
clinical practice, the most established predictor of AAA rupture is maximum AAA diameter …

[HTML][HTML] Association between aortic peak wall stress and rupture index with abdominal aortic aneurysm–related events

TP Singh, JV Moxon, TC Gasser, J Jenkins… - European …, 2023 - Springer
Objective The aim of this study was to assess whether aortic peak wall stress (PWS) and
peak wall rupture index (PWRI) were associated with the risk of abdominal aortic aneurysm …

A computational study of bio-chemo-mechanics of thrombus-laden aneurysms

L Virag, N Horvat, I Karšaj - Journal of the Mechanics and Physics of Solids, 2023 - Elsevier
The role of intraluminal thrombus (ILT) in abdominal aortic aneurysm (AAA) development
has been controversial for decades, yet the researchers and clinicians agree that thrombus …

[HTML][HTML] High-density thrombus and maximum transverse diameter on multi-spiral computed tomography angiography combine to predict abdominal aortic aneurysm …

H Liu, Z Chen, C Tang, H Fan, X Mai, J Cai… - Frontiers in …, 2022 - frontiersin.org
Objective We attempted to measure maximum transverse diameter (MTD) of and CT values
of ILT by using multi-spiral computed tomography angiography (MSCTA) to investigate the …

[HTML][HTML] A systematic review and meta-analysis of the incidence and risk factors for major adverse cardiovascular events in patients with unrepaired abdominal aortic …

C Sharma, TP Singh, S Thanigaimani, D Nastasi… - Biomedicines, 2023 - mdpi.com
Major adverse cardiovascular events (MACE), including myocardial infarction (MI), stroke
and cardiovascular death, cause substantial morbidity and mortality. This review assessed …

[HTML][HTML] Relative Thrombus Burden Ratio Reveals Overproportioned Intraluminal Thrombus Growth—Potential Implications for Abdominal Aortic Aneurysm

J Mulorz, A Mazrekaj, J Sehl, A Arnautovic… - Journal of Clinical …, 2024 - mdpi.com
Background: An intraluminal, non-occlusive thrombus (ILT) is a common feature in an
abdominal aortic aneurysm (AAA). This study investigated the relative progression of ILT vs …

[HTML][HTML] Abdominal aortic aneurysm morphology as an essential criterion for stratifying the risk of aneurysm rupture

N Niklas, P Gutowski, A Kazimierczak… - Journal of Clinical …, 2022 - mdpi.com
The current stratification model of aneurysm rupture seems to be insufficient in some clinical
cases. In our study, we determined the differences in wall structure between ruptured and …